Department of Community-based Rehabilitation Sciences, Graduate School of Biomedical Sciences, Nagasaki University, 1-12-4 Sakamoto, Nagasaki-shi, Nagasaki, 852-8523, Japan.
School of Tropical Medicine and Global Health, Nagasaki University, 1-12-4 Sakamoto, Nagasaki-shi, Nagasaki, 852-8523, Japan.
Int Urogynecol J. 2021 Apr;32(4):887-895. doi: 10.1007/s00192-020-04410-5. Epub 2020 Jul 1.
We assessed the association of pelvic organ prolapse (POP) and urinary incontinence (UI), alone and in combination (POP-UI), and related factors with health-related quality of life (HRQOL) in parous women in Bangladesh.
The study included 357 parous women: 107 with POP alone, 124 with POP-UI, and 126 with UI alone. Data were collected on sociodemographic characteristics, comorbidities, symptom duration, UI severity and type, POP stage, and the 12-item Short-Form Health Survey (SF-12).
The median scores of the SF-12 Physical and Mental Component Summary (PCS and MCS) were 29.1 and 35.7 for POP alone, 28.0 and 35.1 for POP-UI, and 33.9 and 42.0 for UI alone, and there were significant differences among the three groups (p < 0.001). Participants with mixed UI had lower scores on both components than those with stress or urgency UI. UI severity was associated with lower MCS scores, but not with POP stage. Multiple regression analysis showed that the coexistence of POP and UI was associated with significantly worse PCS scores than UI or POP alone and worse MCS scores than UI alone. Age ≥ 46 years was associated with lower PCS scores, and not completing primary school was associated with lower MCS scores.
POP and UI were associated with HRQOL, especially in those who had POP-UI, were older, and had a low educational level, mixed UI, and severe UI. Healthcare providers should understand the significance of these illnesses and address them to improve women's HRQOL.
我们评估了盆腔器官脱垂（POP）和尿失禁（UI）单独和联合（POP-UI）以及相关因素与孟加拉国经产妇健康相关生活质量（HRQOL）的关系。
本研究纳入了 357 名经产妇：107 名单独患有 POP，124 名患有 POP-UI，126 名单独患有 UI。收集了社会人口学特征、合并症、症状持续时间、UI 严重程度和类型、POP 分期以及 12 项简明健康调查（SF-12）。
单独 POP 的 SF-12 身体成分和心理成分综合评分（PCS 和 MCS）中位数分别为 29.1 和 35.7，POP-UI 为 28.0 和 35.1，UI 单独为 33.9 和 42.0，三组之间存在显著差异（p<0.001）。混合 UI 患者的两个评分均低于压力性或急迫性 UI 患者。UI 严重程度与较低的 MCS 评分相关，但与 POP 分期无关。多元回归分析显示，POP 和 UI 的共存与单独 UI 或 POP 相比，PCS 评分显著更差，与单独 UI 相比，MCS 评分更差。年龄≥46 岁与较低的 PCS 评分相关，未完成小学教育与较低的 MCS 评分相关。
POP 和 UI 与 HRQOL 相关，尤其是在那些患有 POP-UI、年龄较大、教育水平较低、混合性 UI 和严重 UI 的患者中。医疗保健提供者应了解这些疾病的重要性，并加以解决，以提高女性的 HRQOL。
