Institute of Health Economics and Health Care Management, Helmholtz Zentrum München, Munich, Germany.
Division of Diabetes Translation, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Appl Health Econ Health Policy. 2020 Oct;18(5):713-726. doi: 10.1007/s40258-020-00565-w.
Lifestyle change interventions (LCI) for prevention of type 2 diabetes are covered by Medicare, but rarely by US Medicaid programs that constitute the largest public payer system in the USA. We estimate the long-term health and economic implications of implementing LCIs in state Medicaid programs.
We compared LCIs modeled after the intervention of the Diabetes Prevention Program versus routine care advice using a decision analytic simulation model and best available data from representative surveys, cohort studies, Medicaid claims data, and the published literature. Target population were non-disability-based adult Medicaid beneficiaries aged 19-64 years at high risk for type 2 diabetes (BMI ≥25 kg/m and HbA1c ≥ 5.7% or fasting plasma glucose ≥ 110 mg/dl) from eight study states (Alabama, California, Connecticut, Florida, Iowa, Illinois, New York, Oklahoma) that represent around 50% of the US Medicaid population. Incremental cost-effectiveness ratios (ICERs) measured in cost per quality-adjusted life years (QALYs) gained, and population cost and health impact were modeled from a healthcare system perspective and a narrow Medicaid perspective.
In the eight selected study states, 1.9 million or 18% of non-disability-based adult Medicaid beneficiaries would belong to the eligible high-risk target population - 66% of them Hispanics or non-Hispanic black. In the base-case analysis, the aggregated 5- and 10-year ICERs are US$226 k/QALY and US$34 k/QALY; over 25 years, the intervention dominates routine care. The 5-, 10-, and 25-year probabilities that the ICERs are below US$50 k (US$100 k)/QALY are 6% (15%), 59% (82%) and 96% (100%). From a healthcare system perspective, initial program investments of US$800 per person would be offset after 13 years and translate to US$548 of savings after 25 years. With a 20% LCI uptake in eligible beneficiaries, this would translate to upfront costs of US$300 million, prevent 260 thousand years of diabetes and save US$205 million over a 25-year time horizon. Cost savings from a narrow Medicaid perspective would be much smaller. Minorities and low-income groups would over-proportionally benefit from LCIs in Medicaid, but the impact on population health and health equity would be marginal.
In the long-term, investments in LCIs for Medicaid beneficiaries are likely to improve health and to decrease healthcare expenditures. However, population health and health equity impact would be low and healthcare expenditure savings from a narrow Medicaid perspective would be much smaller than from a healthcare system perspective.
用于预防 2 型糖尿病的生活方式改变干预措施(LCI)已被医疗保险覆盖,但在美国最大的公共支付系统——美国医疗补助计划中却很少被覆盖。我们评估了在州医疗补助计划中实施 LCI 的长期健康和经济影响。
我们使用决策分析模拟模型和来自代表性调查、队列研究、医疗补助索赔数据和已发表文献的最佳可用数据,将经过糖尿病预防计划干预和常规护理建议的 LCI 进行了比较。目标人群为来自八个研究州(阿拉巴马州、加利福尼亚州、康涅狄格州、佛罗里达州、爱荷华州、伊利诺伊州、纽约州、俄克拉荷马州)的非残疾型成年医疗补助受益人,他们年龄在 19-64 岁之间,有患 2 型糖尿病的高风险(BMI≥25kg/m2 和 HbA1c≥5.7%或空腹血浆葡萄糖≥110mg/dl),占美国医疗补助人口的约 50%。从医疗保健系统的角度和狭义的医疗补助角度,以每获得一个质量调整生命年(QALY)的成本(增量成本效益比)(ICER)来衡量,并对人群成本和健康影响进行建模。
在这八个选定的研究州中,有 190 万或 18%的非残疾型成年医疗补助受益人属于高风险的合格目标人群,其中 66%为西班牙裔或非西班牙裔黑人。在基本分析中,5 年和 10 年的汇总 ICER 分别为 226000 美元/QALY 和 34000 美元/QALY;25 年内,干预措施优于常规护理。ICER 低于 50000 美元(100000 美元)/QALY 的概率为 6%(15%)、59%(82%)和 96%(100%)。从医疗保健系统的角度来看,每人 800 美元的初始项目投资将在 13 年后得到弥补,在 25 年后将转化为 548 美元的节省。如果有 20%的合格受益人参与 LCI,这将需要 3 亿美元的前期成本,在 25 年内可以预防 26 万例糖尿病,并节省 2.05 亿美元。从狭义的医疗补助角度来看,节省的医疗成本要小得多。少数民族和低收入群体将从医疗补助中的 LCI 中获得不成比例的收益,但对人口健康和健康公平的影响将是微不足道的。
从长远来看,对医疗补助受益人的 LCI 投资可能会改善健康并降低医疗支出。然而,人口健康和健康公平的影响将很低,从狭义的医疗补助角度来看,节省的医疗支出将远低于从医疗保健系统角度来看。