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“减少阿尔茨海默病患者残疾”对中重度痴呆患者的效果。

Effectiveness of "Reducing Disability in Alzheimer's Disease" Among Dyads With Moderate Dementia.

机构信息

University of Kansas Alzheimer's Disease Center, Fairway, USA.

University of Missouri-Kansas City, USA.

出版信息

J Appl Gerontol. 2021 Oct;40(10):1163-1171. doi: 10.1177/0733464820934683. Epub 2020 Jul 1.

Abstract

Replications of evidence-based dementia care receiver-caregiver dyad interventions in the community are scarce. We aimed to assess the effectiveness of the Kansas City implementation of Reducing Disability in Alzheimer's Disease (RDAD) among a convenience sample of dyads with moderate dementia, which addressed needs identified by nine participating community agencies. We hypothesized that dyads' mental health and physical activity outcomes would improve from baseline to end-of-treatment. The final analytic sample included 66 dyads. Outcomes improved ( < .01) from pre- to post-intervention: behavioral symptom severity (range 0-36) decreased from 11.3 to 8.6, physical activity increased from 125.0 to 190.0 min/week, caregiver unmet needs (range 0-34) decreased from 10.6 to 5.6, caregiver behavioral symptom distress (0-60) decreased from 15.5 to 10.4, and caregiver strain (0-26) decreased from 11.1 to 9.7. This adapted implementation of RDAD leads to clinically meaningful improvements and might inform scaling-up.

摘要

基于证据的痴呆症护理接受者-护理者对干预措施在社区中的复制很少。我们旨在评估堪萨斯城减少阿尔茨海默病残疾实施(RDAD)在具有中度痴呆的便利样本对中的有效性,该干预措施解决了参与的九个社区机构确定的需求。我们假设,从基线到治疗结束时,护理者的心理健康和身体活动结果会有所改善。最终的分析样本包括 66 对护理者。从干预前到干预后,结果有所改善(<0.01):行为症状严重程度(范围 0-36)从 11.3 降至 8.6,身体活动从 125.0 增加到 190.0 分钟/周,护理者未满足的需求(范围 0-34)从 10.6 降至 5.6,护理者行为症状困扰(0-60)从 15.5 降至 10.4,护理者压力(0-26)从 11.1 降至 9.7。这种适应性实施的 RDAD 带来了有临床意义的改善,并可能为扩大规模提供信息。

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