Ogawa Takenori, Kojima Ikuho, Wakamori Shun, Yoshida Takuya, Murata Takaki, Sakamoto Maya, Ohkoshi Akira, Nakanome Ayako, Endo Hidenori, Endo Toshiki, Usubuchi Hajime, Katori Yukio
Department of Otolaryngology-Head and Neck Surgery, Tohoku University Hospital, Sendai, Japan.
Head and Neck Cancer Center, Tohoku University Hospital, Sendai, Japan.
Head Neck. 2020 Oct;42(10):2896-2904. doi: 10.1002/hed.26336. Epub 2020 Jul 1.
The usefulness of apparent diffusion coefficient (ADC) and diffusion-weighted magnetic resonance imaging (DWI) in the detection of malignant tumors has been reported. The purpose of this study is to clarify the role of ADC and DWI for diagnosis of skull base tumors.
A total of 27 patients with head and neck tumors with skull base invasions undergoing skull base surgery were enrolled in this study. Pathological findings of dural invasion and bone invasion were compared with the diagnostic imaging.
Advanced magnetic resonance imaging techniques revealed that ADC values in regions of pathological bone and dural invasions were significantly lower than in regions of no invasion. The area under the curve of ADC in bone invasions and dural invasions were 0.957 and 0.894, respectively.
Our findings indicate that ADC and DWI are useful tools for the diagnosis of head and neck tumors with skull base invasion.
表观扩散系数（ADC）和扩散加权磁共振成像（DWI）在恶性肿瘤检测中的作用已有报道。本研究的目的是阐明ADC和DWI在颅底肿瘤诊断中的作用。
本研究纳入了27例接受颅底手术的头颈部肿瘤伴颅底侵犯患者。将硬脑膜侵犯和骨侵犯的病理结果与诊断性影像学结果进行比较。
先进的磁共振成像技术显示，病理骨侵犯和硬脑膜侵犯区域的ADC值明显低于无侵犯区域。骨侵犯和硬脑膜侵犯中ADC的曲线下面积分别为0.957和0.894。
我们的研究结果表明，ADC和DWI是诊断头颈部肿瘤伴颅底侵犯的有用工具。
