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新加坡一家新冠肺炎重症监护病房患者的肺部超声检查及其在疫情中的潜在临床应用综述

Lung ultrasound in a Singapore COVID-19 intensive care unit patient and a review of its potential clinical utility in pandemic.

作者信息

Peh Wee Ming, Ting Chan Steffi Kang, Lee Yi Lin, Gare Pravin Shivaji, Ho Vui Kian

机构信息

Department of General Medicine and Intensive Care Medicine, Seng Kang General Hospital , Singapore.

Department of Anaesthesiology, Singapore General Hospital , Singapore.

出版信息

J Ultrason. 2020;20(81):e154-e158. doi: 10.15557/JoU.2020.0025. Epub 2020 Jun 15.

DOI:10.15557/JoU.2020.0025
PMID:32609971
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7409542/
Abstract

Point-of-care bedside lung ultrasound is a diagnostic adjunct in the management of respiratory diseases. We describe the clinical progress and lung ultrasound findings of a Singaporean COVID-19 intensive care unit patient who was diagnosed with COVID-19 infection. The clinical course of one COVID-19 patient managed in the intensive care unit was traced. The patient was diagnosed with COVID-19 virus infection and intubated after developing respiratory failure. Serial point-of-care bedside lung ultrasound was performed by the managing intensivist daily, and correlated with the clinical progress and chest X-ray imaging done for the patient. The patient exhibited lung ultrasound findings consistent with that described for viral pneumonias. This included numerous B-lines and subpleural consolidations with disrupted pleural lines distributed symmetrically, predominantly in bilateral upper BLUE points, and lower BLUE points bilaterally. Coalescing B-lines leading on to the development of bilateral "white lung" were associated with worsening acute respiratory distress syndrome. An increased density or reduction of the B-lines was associated with clinical improvement or deterioration, respectively. Trained clinicians, who are familiar with point-of-care lung ultrasonography, may consider point-of-care bedside ultrasound as an important adjunct to history and physical examination for the diagnosis and management of COVID-19 when advanced imaging is not available because of logistical reasons or infectious control. This applies in particular to cases where resources are limited, and patient transfers to facilities offering such services may prove hazardous. Point-of-care bedside lung ultrasound is a diagnostic adjunct in the management of respiratory diseases. We describe the clinical progress and lung ultrasound findings of a Singaporean COVID-19 intensive care unit patient who was diagnosed with COVID-19 infection. The clinical course of one COVID-19 patient managed in the intensive care unit was traced. The patient was diagnosed with COVID-19 virus infection and intubated after developing respiratory failure. Serial point-of-care bedside lung ultrasound was performed by the managing intensivist daily, and correlated with the clinical progress and chest X-ray imaging done for the patient. The patient exhibited lung ultrasound findings consistent with that described for viral pneumonias. This included numerous B-lines and subpleural consolidations with disrupted pleural lines distributed symmetrically, predominantly in bilateral upper BLUE points, and lower BLUE points bilaterally. Coalescing B-lines leading on to the development of bilateral “white lung” were associated with worsening acute respiratory distress syndrome. An increased density or reduction of the B-lines was associated with clinical improvement or deterioration, respectively. Trained clinicians, who are familiar with point-of-care lung ultrasonography, may consider point-of-care bedside ultrasound as an important adjunct to history and physical examination for the diagnosis and management of COVID-19 when advanced imaging is not available because of logistical reasons or infectious control. This applies in particular to cases where resources are limited, and patient transfers to facilities offering such services may prove hazardous.

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04b2/7409542/0ff246d29e43/jou-20-81-e154-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04b2/7409542/27f4f031eddb/jou-20-81-e154-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04b2/7409542/96fb92d6432d/jou-20-81-e154-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04b2/7409542/2702247ac058/jou-20-81-e154-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04b2/7409542/0ff246d29e43/jou-20-81-e154-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04b2/7409542/27f4f031eddb/jou-20-81-e154-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04b2/7409542/96fb92d6432d/jou-20-81-e154-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04b2/7409542/2702247ac058/jou-20-81-e154-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04b2/7409542/0ff246d29e43/jou-20-81-e154-g004.jpg
摘要

床旁即时肺部超声是呼吸系统疾病管理中的一种诊断辅助手段。我们描述了一名被诊断为新冠病毒感染的新加坡新冠重症监护病房患者的临床病程及肺部超声检查结果。追踪了一名在重症监护病房接受治疗的新冠患者的临床病程。该患者被诊断为新冠病毒感染,在出现呼吸衰竭后进行了插管。主治重症监护医生每天进行床旁即时肺部超声检查,并将其与患者的临床病程及胸部X光影像进行对比。该患者的肺部超声检查结果与病毒性肺炎相符。这包括大量B线以及胸膜下实变,胸膜线中断,呈对称分布,主要位于双侧上蓝点及双侧下蓝点。融合的B线导致双侧“白肺”的出现与急性呼吸窘迫综合征的恶化相关。B线密度增加或减少分别与临床改善或恶化相关。熟悉床旁即时肺部超声检查的经过培训的临床医生,在因后勤原因或感染控制无法进行高级影像检查时,可将床旁即时超声视为新冠诊断和管理中病史及体格检查的重要辅助手段。这尤其适用于资源有限的情况,以及将患者转至提供此类服务的机构可能存在风险的情况。床旁即时肺部超声是呼吸系统疾病管理中的一种诊断辅助手段。我们描述了一名被诊断为新冠病毒感染的新加坡新冠重症监护病房患者的临床病程及肺部超声检查结果。追踪了一名在重症监护病房接受治疗的新冠患者的临床病程。该患者被诊断为新冠病毒感染,在出现呼吸衰竭后进行了插管。主治重症监护医生每天进行床旁即时肺部超声检查,并将其与患者的临床病程及胸部X光影像进行对比。该患者的肺部超声检查结果与病毒性肺炎相符。这包括大量B线以及胸膜下实变,胸膜线中断,呈对称分布,主要位于双侧上蓝点及双侧下蓝点。融合的B线导致双侧“白肺”的出现与急性呼吸窘迫综合征的恶化相关。B线密度增加或减少分别与临床改善或恶化相关。熟悉床旁即时肺部超声检查的经过培训的临床医生,在因后勤原因或感染控制无法进行高级影像检查时,可将床旁即时超声视为新冠诊断和管理中病史及体格检查的重要辅助手段。这尤其适用于资源有限的情况,以及将患者转至提供此类服务的机构可能存在风险的情况。

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