Department of Radiology, Beijing Ditan Hospital, Capital Medical University, China.
Jpn J Infect Dis. 2021 Jan 22;74(1):1-6. doi: 10.7883/yoken.JJID.2020.264. Epub 2020 Jun 30.
In total, 11 asymptomatic carriers who underwent nasal or oropharyngeal swab tests for SARS-CoV-2 after being in close contact with patients who developed symptomatic 2019 coronavirus disease (COVID-19) were enrolled in this study. The chest multidetector computed tomography (CT) images of the enrolled patients were qualitatively and quantitatively analyzed. The findings of the first chest CT were normal in 3 (27.3%) patients, 2 of whom were aged below 15 years. The lesions of 2 (18.2%) patients involved 1 lobe with unifocal presence. Subpleural lesions were observed in 7 (63.6%) patients. Ground glass opacity (GGO) was the most common sign observed in 7 (63.6%) patients. Crazy-paving pattern and consolidation were detected in 2 (18.2%) and 4 (36.4%) patients, respectively. Based on deep learning and quantitative analysis, the mean volume of intrapulmonary lesions in the first CT image was 85.73 ± 84.46 cm. In patients with positive findings on CT images, the average interval between positive real-time reverse transcriptase polymerase chain reaction assay and peak volume on CT images was 5.1 ± 3.1 days. In conclusion, typical CT findings can be detected in over 70% of asymptomatic SARS-CoV-2 carriers. The initial presentation is typically GGO along the subpleural regions and bronchi, which absorbs in approximately 5 days.
共有 11 名无症状感染者在与出现症状的 2019 年冠状病毒病（COVID-19）患者密切接触后，接受了 SARS-CoV-2 的鼻拭子或咽拭子检测，这些无症状感染者被纳入了本研究。对纳入患者的胸部多层 CT 图像进行了定性和定量分析。3 名（27.3%）患者的首次胸部 CT 检查结果正常，其中 2 名年龄低于 15 岁。2 名（18.2%）患者的病变仅累及 1 个肺叶，呈局灶性分布。7 名（63.6%）患者存在胸膜下病变。7 名（63.6%）患者最常见的 CT 征象是磨玻璃密度影（GGO）。2 名（18.2%）和 4 名（36.4%）患者分别检测到铺路石征和实变。基于深度学习和定量分析，首次 CT 图像中肺内病变的平均体积为 85.73±84.46cm。在 CT 图像有阳性发现的患者中，实时逆转录聚合酶链反应检测阳性与 CT 图像峰值体积之间的平均间隔为 5.1±3.1 天。总之，超过 70%的无症状 SARS-CoV-2 感染者可检测到典型的 CT 表现。初始表现通常是沿着胸膜下区域和支气管的磨玻璃影，大约 5 天左右吸收。
