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冠状动脉手术对左心室功能、节段性室壁运动及运动性心肌缺血的影响。

Effects of coronary artery surgery on left ventricular performance, segmental wall movement, and exertional ischaemia.

作者信息

Hamouratidis N D, Handler C E, Pipilis A, Fiandra A, Deverall P B, Yates A K

机构信息

Department of Cardiology, Guy's Hospital, London.

出版信息

Br Heart J. 1988 Jul;60(1):23-9. doi: 10.1136/hrt.60.1.23.

Abstract

The effects of coronary artery surgery on left ventricular performance were assessed serially by echocardiography and treadmill exercise testing in 54 patients. Patients were assessed one day before operation and again before patients left hospital (mean 10 days after operation) and one month and six months after operation. At the predischarge assessment, 41 (77%) patients showed new abnormalities of left ventricular segmental wall movement, chiefly anteroseptal hypokinesia with hyperkinesia of the posterolateral segment. Although there were no significant changes in anteroseptal wall thickening after operation, there was a significant increase in posterior wall thickening at all postoperative assessments. The frequency of this abnormality decreased progressively after operation; it persisted in 19 (35%) patients at six months. Left ventricular fractional shortening decreased after operation and at one month was significantly less than before operation. There were no significant changes in left ventricular diastolic diameter during the study. Haemodynamic function during exercise, the duration of exercise, and features of reversible myocardial ischaemia all improved progressively and significantly after coronary artery surgery. Abnormalities in left ventricular segmental wall movement and thickening commonly develop early after coronary artery surgery but tend to resolve by six months and do not seem to impair left ventricular contractility at rest or exercise performance and haemodynamic function. Recognition of these echocardiographic changes may be clinically important in the assessment of patients after cardiac surgery.

摘要

通过超声心动图和跑步机运动试验对54例患者冠状动脉手术对左心室功能的影响进行了系列评估。在手术前一天、患者出院前(平均术后10天)、术后1个月和6个月对患者进行评估。在出院前评估时,41例(77%)患者出现左心室节段性壁运动新异常,主要是前间隔运动减弱伴后外侧节段运动增强。虽然术后前间隔壁增厚无显著变化,但在所有术后评估中后壁增厚均显著增加。这种异常的发生率在术后逐渐降低;6个月时仍有19例(35%)患者持续存在。术后左心室缩短分数降低,术后1个月时显著低于术前。研究期间左心室舒张直径无显著变化。冠状动脉手术后运动时的血流动力学功能、运动持续时间和可逆性心肌缺血特征均逐渐且显著改善。冠状动脉手术后早期常出现左心室节段性壁运动和增厚异常,但往往在6个月时消失,似乎不影响静息或运动时的左心室收缩力以及血流动力学功能。认识到这些超声心动图变化在心脏手术后患者的评估中可能具有重要临床意义。

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