Taylor N C, Barber R, Crossland P, Wraight E P, English T A, Petch M C
Br Heart J. 1985 Aug;54(2):145-52. doi: 10.1136/hrt.54.2.145.
Fourteen consecutive patients undergoing left ventricular aneurysmectomy and coronary artery bypass grafting were studied by multiple gated ventricular scintigraphy at rest and during exercise before and at six weeks and six months after surgery. All had congestive heart failure and 12 angina pectoris. Before operation left ventricular ejection fraction fell significantly with exercise, as did the regional wall motion score. Six weeks after surgery all surviving patients were free of angina, with an improvement in functional class; the total exercise workload improved significantly, but resting left ventricular ejection fraction was unchanged; the regional wall motion score improved in both the anterior and left anterior oblique projections, although extensive areas of abnormal contraction persisted. Exercise left ventricular ejection fraction improved significantly after operation at six weeks, and previous exercise induced abnormalities of regional contraction were abolished. Six months after operation angina pectoris had recurred in one patient, but there was no further change in ventricular function in the remainder. Although resting ejection fraction is not improved, symptoms, exercise workload, and exercise ventricular function can be improved by aneurysmectomy and coronary artery bypass grafting, but the respective contribution of these two procedures remains uncertain.
对14例连续接受左心室室壁瘤切除术和冠状动脉搭桥术的患者,在术前、术后6周和6个月时进行静息和运动状态下的多门控心室闪烁扫描研究。所有患者均有充血性心力衰竭,12例有稳定型心绞痛。术前运动时左心室射血分数显著下降,节段性室壁运动评分也下降。术后6周,所有存活患者心绞痛消失,心功能分级改善;总运动负荷显著提高,但静息左心室射血分数未变;在前位和左前斜位投影中,节段性室壁运动评分均有改善,尽管仍有广泛的异常收缩区域。术后6周运动时左心室射血分数显著改善,术前运动诱发的节段性收缩异常消失。术后6个月,1例患者复发心绞痛,但其余患者心室功能无进一步变化。虽然静息射血分数未改善,但室壁瘤切除术和冠状动脉搭桥术可改善症状、运动负荷和运动时的心室功能,但这两种手术各自的作用仍不确定。