通过多门控心室闪烁造影术评估冠状动脉搭桥术对左心室功能的影响。
Effects of coronary artery bypass grafting on left ventricular function assessed by multiple gated ventricular scintigraphy.
作者信息
Taylor N C, Barber R W, Crossland P, English T A, Wraight E P, Petch M C
出版信息
Br Heart J. 1983 Aug;50(2):149-56. doi: 10.1136/hrt.50.2.149.
The effect of coronary artery bypass grafting on global left ventricular ejection fraction and regional contraction was studied in 56 consecutive patients with chronic stable angina pectoris by means of multiple gated ventricular scintigraphy at rest and during dynamic supine exercise before and six weeks after myocardial revascularisation. Before operation, exercise induced a significant fall in ejection fraction and regional wall motion score. Six weeks after operation 52 patients were symptomless. Resting ejection fraction and regional wall motion score were unchanged but during exercise ejection fraction increased significantly, and the previous exercise induced regional wall motion abnormalities were abolished. All four patients with persisting angina showed the same pattern as before operation, with a fall in left ventricular ejection fraction and regional wall motion score during exercise. Multiple gated ventricular scintigraphy affords a safe, objective, reproducible, and non-invasive means of assessing serial ventricular function at rest and during exercise in patients with ischaemic heart disease. The technique confirms that coronary bypass surgery abolishes exercise induced abnormalities of left ventricular function, but has no influence on resting function.
通过多门控心室闪烁显像技术，对56例连续性慢性稳定型心绞痛患者在心肌血运重建术前、术后六周静息状态及动态仰卧运动时的左心室整体射血分数及局部收缩功能进行了研究。术前，运动可导致射血分数及局部室壁运动评分显著下降。术后六周，52例患者无症状。静息射血分数及局部室壁运动评分未变，但运动时射血分数显著增加，且之前运动诱发的局部室壁运动异常消失。所有4例持续心绞痛患者表现出与术前相同的模式，运动时左心室射血分数及局部室壁运动评分下降。多门控心室闪烁显像技术为评估缺血性心脏病患者静息及运动时的系列心室功能提供了一种安全、客观、可重复且无创的方法。该技术证实冠状动脉搭桥手术可消除运动诱发的左心室功能异常，但对静息功能无影响。
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