Should Therapeutic Monitoring of Vancomycin Based on Area under the Curve Become Standard Practice for Patients with Confirmed or Suspected Methicillin-Resistant Infection?
出版信息
Can J Hosp Pharm. 2020 May-Jun;73(3):232-237. Epub 2020 Jun 1.
Abstract
摘要
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Should Therapeutic Monitoring of Vancomycin Based on Area under the Curve Become Standard Practice for Patients with Confirmed or Suspected Methicillin-Resistant Infection?基于曲线下面积的万古霉素治疗监测是否应成为确诊或疑似耐甲氧西林感染患者的标准治疗方法？
Can J Hosp Pharm. 2020 May-Jun;73(3):232-237. Epub 2020 Jun 1.
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Area under the concentration-time curve to minimum inhibitory concentration ratio as a predictor of vancomycin treatment outcome in methicillin-resistant Staphylococcus aureus bacteraemia.浓度-时间曲线下面积与最低抑菌浓度比值作为预测耐甲氧西林金黄色葡萄球菌菌血症万古霉素治疗结果的指标。
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J Clin Pharmacol. 2019 Feb;59(2):198-205. doi: 10.1002/jcph.1323. Epub 2018 Oct 29.
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Impact of area under the concentration-time curve to minimum inhibitory concentration ratio on vancomycin treatment outcomes in methicillin-resistant Staphylococcus aureus bacteraemia.浓度-时间曲线下面积与最低抑菌浓度比值对耐甲氧西林金黄色葡萄球菌菌血症万古霉素治疗结局的影响。
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Therapeutic monitoring of vancomycin for serious methicillin-resistant Staphylococcus aureus infections: A revised consensus guideline and review by the American Society of Health-System Pharmacists, the Infectious Diseases Society of America, the Pediatric Infectious Diseases Society, and the Society of Infectious Diseases Pharmacists.针对耐甲氧西林金黄色葡萄球菌严重感染的万古霉素治疗监测：美国卫生系统药师协会、美国传染病学会、儿科传染病学会及传染病药师学会的修订共识指南及综述
Am J Health Syst Pharm. 2020 May 19;77(11):835-864. doi: 10.1093/ajhp/zxaa036.
2
Effect of Vancomycin or Daptomycin With vs Without an Antistaphylococcal β-Lactam on Mortality, Bacteremia, Relapse, or Treatment Failure in Patients With MRSA Bacteremia: A Randomized Clinical Trial.万古霉素或达托霉素联合与不联合抗葡萄球菌β-内酰胺类药物治疗耐甲氧西林金黄色葡萄球菌菌血症患者的死亡率、菌血症、复发或治疗失败的影响：一项随机临床试验。
JAMA. 2020 Feb 11;323(6):527-537. doi: 10.1001/jama.2020.0103.
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AUC- vs. Trough-Guided Monitoring of Vancomycin in Infants.AUC- 与谷浓度指导下的婴儿万古霉素监测。
Indian J Pediatr. 2020 May;87(5):359-364. doi: 10.1007/s12098-019-03162-5. Epub 2020 Jan 27.
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Correlation of the vancomycin 24-h area under the concentration-time curve (AUC) and trough serum concentration in children with severe infection: A clinical pharmacokinetic study.儿童严重感染患者万古霉素 24 小时浓度-时间曲线下面积（AUC）与谷浓度的相关性：一项临床药代动力学研究。
Int J Infect Dis. 2020 Mar;92:151-159. doi: 10.1016/j.ijid.2019.12.036. Epub 2020 Jan 11.
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Inhaled amikacin adjunctive to intravenous standard-of-care antibiotics in mechanically ventilated patients with Gram-negative pneumonia (INHALE): a double-blind, randomised, placebo-controlled, phase 3, superiority trial.吸入性阿米卡星辅助治疗机械通气革兰氏阴性菌肺炎患者静脉标准治疗抗生素（INHALE）：一项双盲、随机、安慰剂对照、3 期优效性试验。
Lancet Infect Dis. 2020 Mar;20(3):330-340. doi: 10.1016/S1473-3099(19)30574-2. Epub 2019 Dec 19.
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Vancomycin area under the curve to minimum inhibitory concentration ratio predicting clinical outcome: a systematic review and meta-analysis with pooled sensitivity and specificity.万古霉素曲线下面积与最小抑菌浓度比值预测临床结局的系统评价和荟萃分析：合并敏感性和特异性。
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Population pharmacokinetics of vancomycin in obesity: Finding the optimal dose for (morbidly) obese individuals.肥胖人群中万古霉素的群体药代动力学：寻找（病态）肥胖个体的最佳剂量。
Br J Clin Pharmacol. 2020 Feb;86(2):303-317. doi: 10.1111/bcp.14144. Epub 2020 Jan 7.
8
Pharmacist Survey: Pharmacist Perception of Vancomycin Area Under the Curve Therapeutic Drug Monitoring.药剂师调查：药剂师对万古霉素曲线下面积治疗药物监测的认知
J Pharm Pract. 2021 Apr;34(2):272-278. doi: 10.1177/0897190019867494. Epub 2019 Aug 18.
9
Optimizing Vancomycin Use Through 2-Point AUC-Based Therapeutic Drug Monitoring in Pediatric Patients.通过基于 AUC 的两点治疗药物监测优化万古霉素在儿科患者中的使用。
J Clin Pharmacol. 2019 Dec;59(12):1597-1605. doi: 10.1002/jcph.1498. Epub 2019 Jul 24.
10
The Emperor's New Clothes: PRospective Observational Evaluation of the Association Between Initial VancomycIn Exposure and Failure Rates Among ADult HospitalizEd Patients With Methicillin-resistant Staphylococcus aureus Bloodstream Infections (PROVIDE).皇帝的新装：对万古霉素初始暴露与耐甲氧西林金黄色葡萄球菌血流感染成年住院患者失败率之间关系的前瞻性观察性评估（PROVIDE）
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