Ambinder Emily B, Werner Rudolf A, Rowe Steven P
Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins Medical Institutions, 601 N. Caroline Street, Baltimore 21287, MD, USA.
Department of Nuclear Medicine, Hannover Medical School, Hannover, Germany.
Radiol Case Rep. 2020 Jun 25;15(8):1344-1347. doi: 10.1016/j.radcr.2020.05.054. eCollection 2020 Aug.
We present a case of a 53-year-old woman with metastatic neuroendocrine tumor, presumed primary in the small intestine with metastases to the liver and mesenteric lymph nodes. The patient was being treated with lanreotide and followed with somatostatin receptor (SSTR)-targeted 68Ga-labeled 1,4,7,10-tetraazacyclododecane-', '','''-tetraacetic acid-d-Phe(1)-Tyr(3)-octreotate (Ga-DOTATATE) positron emission tomography - computed tomography (PET/CT). On a follow-up exam, the patient's primary and metastatic disease had improved but she had new Ga-DOTATATE-avid lesions in the right breast and right axilla. Subsequent breast imaging workup and biopsy demonstrated a primary breast cancer and axillary lymph node metastasis.
我们报告一例53岁女性转移性神经内分泌肿瘤患者，推测原发于小肠，已转移至肝脏和肠系膜淋巴结。该患者正在接受兰瑞肽治疗，并采用靶向生长抑素受体（SSTR）的68Ga标记的1,4,7,10-四氮杂环十二烷-N,N',N'',N'''-四乙酸-d-苯丙氨酸（1）-酪氨酸（3）-奥曲肽（Ga-DOTATATE）正电子发射断层扫描-计算机断层扫描（PET/CT）进行随访。在一次随访检查中，患者的原发性和转移性疾病有所改善，但右乳和右腋窝出现了新的Ga-DOTATATE摄取病灶。随后的乳腺影像学检查和活检显示为原发性乳腺癌和腋窝淋巴结转移。
