Thomas P R, Mansfield M D, Hendry W F, Peckham M J
Br J Surg. 1977 May;64(5):352-4. doi: 10.1002/bjs.1800640515.
Seminal analyses have been performed in 14 patients who have received radiation therapy following unilateral orchidectomy for testicular tumours. In patients receiving scrotal in addition to para-aortic and pelvic lymph node irradiation azoospermia occurred in 17 out 18 specimens examined, whereas in those patients not requiring scrotal irradiation, restoration of spermatogenesis occurred. The difference is a result of the increased dose of radiation received by the remaining testicle when the contralateral side of the scrotum is irradiated. Following scrotal aspiration, trans-scrotal biopsy or scrotal orchidectomy for testicular tumour, the scrotum becomes a possible site of recurrence and it should be electively irradiated. In order to give the patient the best chance of preserving fertility it is essential that scrotal interference in the management of testicular tumours must be avoided.
对14例因睾丸肿瘤接受单侧睾丸切除术后接受放射治疗的患者进行了开创性分析。在接受阴囊以及腹主动脉旁和盆腔淋巴结照射的患者中，18份检查样本中有17份出现无精子症，而在那些不需要阴囊照射的患者中，精子发生得以恢复。这种差异是由于阴囊对侧接受照射时，剩余睾丸所接受的辐射剂量增加所致。在因睾丸肿瘤进行阴囊抽吸、经阴囊活检或阴囊睾丸切除术后，阴囊成为可能的复发部位，应进行选择性照射。为了给患者保留生育能力的最佳机会，必须避免在睾丸肿瘤管理中对阴囊进行干预。
