Virginia Commonwealth University, McGuire VA Medical Center, Richmond, Virginia, USA.
Hospital of South West Jutland, Esbjerg, Denmark.
Am J Gastroenterol. 2020 Jul;115(7):989-1002. doi: 10.14309/ajg.0000000000000603.
Management of hepatic encephalopathy (HE) remains challenging from a medical and psychosocial perspective. Members of the International Society for Hepatic Encephalopathy and Nitrogen Metabolism recognized 5 key unresolved questions in HE management focused on (i) driving, (ii) ammonia levels in clinical practice, (iii) testing strategies for covert or minimal HE, (iv) therapeutic options, and (v) nutrition and patient-reported outcomes. The consensus document addresses these topical issues with a succinct review of the literature and statements that critically evaluate the current science and practice, laying the groundwork for future investigations.
从医学和社会心理角度来看，肝性脑病（HE）的管理仍然具有挑战性。国际肝脏性脑病和氮代谢学会的成员确定了 5 个HE 管理方面未解决的关键问题，重点关注（i）驾驶，（ii）临床实践中的氨水平，（iii）隐匿性或轻微 HE 的检测策略，（iv）治疗选择，以及（v）营养和患者报告的结局。这份共识文件通过简洁地回顾文献和批判性评估当前科学和实践，解决了这些热门问题，为未来的研究奠定了基础。
