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SARS-CoV-2 感染患者的消化道症状与住院的关系。

Association of Digestive Symptoms and Hospitalization in Patients With SARS-CoV-2 Infection.

机构信息

Division of Gastroenterology and Hepatology, Stanford University School of Medicine, Redwood City, California, USA.

Department of Epidemiology and Population Health, Stanford University School of Medicine, Stanford, California, USA.

出版信息

Am J Gastroenterol. 2020 Jul;115(7):1129-1132. doi: 10.14309/ajg.0000000000000712.

DOI:10.14309/ajg.0000000000000712
PMID:32618665
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7302101/
Abstract

INTRODUCTION

High rates of concurrent gastrointestinal manifestations have been noted in patients with corona virus disease 2019 (COVID-19); however, the association between these digestive manifestations and need for hospitalization has not been established.

METHODS

This is a retrospective review of consecutive patients diagnosed with COVID-19. A total of 207 patients were identified; 34.5% of patients noted concurrent gastrointestinal symptoms, with 90% of gastrointestinal symptoms being mild.

RESULTS

In a multivariate regression model controlled for demographics and disease severity, an increased risk of hospitalization was noted in patients with any digestive symptom (adjusted odds ratio 4.84, 95% confidence interval: 1.68-13.94).

DISCUSSION

The presence of digestive symptoms in COVID-19 is associated with a need for hospitalization.

摘要

简介

新型冠状病毒病 2019(COVID-19)患者常伴有胃肠道表现;然而,这些消化系统表现与住院需求之间的关系尚未确定。

方法

这是一项对连续确诊 COVID-19 患者的回顾性研究。共确定了 207 例患者;34.5%的患者存在胃肠道症状,90%的胃肠道症状为轻度。

结果

在调整了人口统计学和疾病严重程度的多变量回归模型中,存在任何消化系统症状的患者住院风险增加(调整后的优势比 4.84,95%置信区间:1.68-13.94)。

讨论

COVID-19 患者存在消化系统症状与住院需求相关。

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2
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Gastroenterology. 2020 Aug;159(2):775-777. doi: 10.1053/j.gastro.2020.04.008. Epub 2020 Apr 10.
3
Structural basis for the recognition of SARS-CoV-2 by full-length human ACE2.全长人血管紧张素转化酶 2 识别 SARS-CoV-2 的结构基础。
Science. 2020 Mar 27;367(6485):1444-1448. doi: 10.1126/science.abb2762. Epub 2020 Mar 4.
4
Clinical Characteristics of Coronavirus Disease 2019 in China.《中国 2019 年冠状病毒病临床特征》
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