Department of Gastroenterology, Dokuz Eylül University Faculty of Medicine, İzmir, Turkey.
Department of Infectious Diseases and Clinical Microbiology, Dokuz Eylül University Faculty of Medicine, İzmir, Turkey.
Turk J Gastroenterol. 2022 Nov;33(11):955-963. doi: 10.5152/tjg.2022.21484.
In patients with coronavirus disease 2019, the gastrointestinal symptoms have been reported increasingly in addition to the respiratory system symptoms. The studies show that the prevalence of gastrointestinal system symptoms and how the gastrointestinal system contributes to the severity and prognosis of the disease is still not clear. This study aims to find the prevalence of gastrointestinal symptoms and the correlation between the gastrointestinal symptoms and the clinical results in hospitalized patients diagnosed with coronavirus disease 2019.
This study retrospectively analyzes patients diagnosed with coronavirus disease 2019 and hospitalized in the pandemic unit between March 2020 and August 2020 and compares their demographic and clinical characteristics, laboratory and radiologic findings, coronavirus disease 2019 treatments received, the clinical course of the disease, and the gastrointestinal symptoms.
In our study, we included 322 patients diagnosed with coronavirus disease 2019 and hospitalized; 39 patients (12.1%) were admitted to the hospital with at least one gastrointestinal symptom (nausea and vomiting, diarrhea, abdominal pain, and the loss of taste). Nausea and vomiting are the most common gastrointestinal symptoms with a prevalence of 7.1%, followed by diarrhea with 2.8%, the loss of taste with 2.2%, and abdominal pain with 1.5%. The mean age and D-dimer levels of the patients showing gastrointestinal symptoms were lower than those who did not have any gastrointestinal symptoms. We did not find a significant correlation between the presence of the gastrointestinal symptoms and the severity of the disease, treatment received, risk of acute respiratory distress syndrome and septic shock, admission to the intensive care unit, the need for mechanical ventilation, the mortality rate or the length of hospitalization in the medical floor or the intensive care unit.
In this study, we observed that 12.1% of coronavirus disease 2019 patients apply to the hospital due to gastrointestinal symptoms. Furthermore, the gastrointestinal symptoms do not seem to affect the severity and the course of the disease, it is important to identify coronavirus disease 2019 patients showing unusual symptoms such as the gastrointestinal symptoms at an early stage to protect healthcare professionals from infection risk.
在 2019 年冠状病毒病患者中，除呼吸系统症状外，胃肠道症状也越来越多地被报道。研究表明，胃肠道系统症状的发生率以及胃肠道系统对疾病严重程度和预后的影响尚不清楚。本研究旨在发现住院 2019 年冠状病毒病患者胃肠道症状的发生率以及胃肠道症状与临床结果之间的相关性。
本研究回顾性分析了 2020 年 3 月至 2020 年 8 月期间在大流行病房住院的 2019 年冠状病毒病患者，并比较了他们的人口统计学和临床特征、实验室和影像学检查结果、接受的 2019 年冠状病毒病治疗、疾病的临床过程以及胃肠道症状。
在本研究中，我们纳入了 322 例诊断为 2019 年冠状病毒病并住院的患者；39 例（12.1%）患者因至少一种胃肠道症状（恶心和呕吐、腹泻、腹痛和味觉丧失）住院。恶心和呕吐是最常见的胃肠道症状，其患病率为 7.1%，其次是腹泻（2.8%）、味觉丧失（2.2%）和腹痛（1.5%）。出现胃肠道症状的患者的平均年龄和 D-二聚体水平低于无胃肠道症状的患者。我们没有发现胃肠道症状的存在与疾病严重程度、所接受的治疗、急性呼吸窘迫综合征和感染性休克的风险、入住重症监护病房、需要机械通气、死亡率或在医疗病房或重症监护病房的住院时间之间存在显著相关性。
在本研究中，我们观察到 12.1%的 2019 年冠状病毒病患者因胃肠道症状就诊于医院。此外，胃肠道症状似乎不会影响疾病的严重程度和病程，早期识别出现不典型症状（如胃肠道症状）的 2019 年冠状病毒病患者对于保护医护人员免受感染风险非常重要。
