Konradsen L, Nexø E
Department of Clinical Chemistry, Central Hospital, Hillerød, Denmark.
Regul Pept. 1988 Jun;21(3-4):197-203. doi: 10.1016/0167-0115(88)90002-x.
The substance concentration of epidermal growth factor immunoreactivity (EGF IR) and certain other components were studied in plasma, serum and urine from 25 individuals before and after a 2 h cross-country run. The substance concentration of plasma EGF IR increased from a median of 0.10 nM (range 0.04-0.26 nM) to a median of 0.16 nM (range 0.10-0.36 nM) after 2 h of exercise, while serum EGF showed no change. The values obtained for B-platelets were a median of 192 x 10(9)/litre (range 109-282 x 10(9)/litre) before the run, and a median of 265 x 10(9)/litre (range 216-387 x 10(9)/litre) after the run. No correlation was observed between the values obtained for B-platelets and the values for plasma or serum EGF IR. The substance concentration of EGF IR in urine increased from a median of 3.2 nM (range 0.5-7.7 nM) to a median of 7.0 nM (range 1.5-15.7 nM) after the run. Expressed relative to the output of carbamide the output of urinary EGF IR increased with a median factor of 2 following the run. Expressed relative to the output of creatinine no increase was observed.
对25名个体在进行2小时越野跑前后的血浆、血清和尿液中的表皮生长因子免疫反应性（EGF IR）物质浓度及某些其他成分进行了研究。运动2小时后，血浆EGF IR物质浓度从中位数0.10 nM（范围0.04 - 0.26 nM）增加到中位数0.16 nM（范围0.10 - 0.36 nM），而血清EGF无变化。跑步前B血小板的值为中位数192×10⁹/升（范围109 - 282×10⁹/升），跑步后为中位数265×10⁹/升（范围216 - 387×10⁹/升）。未观察到B血小板的值与血浆或血清EGF IR的值之间存在相关性。跑步后尿液中EGF IR的物质浓度从中位数3.2 nM（范围0.5 - 7.7 nM）增加到中位数7.0 nM（范围1.5 - 15.7 nM）。相对于尿素的排出量，跑步后尿液EGF IR的排出量增加，中位数因子为2。相对于肌酐的排出量，未观察到增加。
