Cohen M L, Ming R H, Gogel H K, Davis M, Pitcher J L
Department of Internal Medicine, University of New Mexico School of Medicine, Albuquerque 87131.
J Clin Gastroenterol. 1988 Apr;10(2):210-2. doi: 10.1097/00004836-198804000-00022.
Phenylbutazone (PBZ) is a nonsteroidal antiinflammatory drug (NSAID) that is not commonly prescribed due to the high incidence of serious adverse reactions. However, it is still used extensively in equine medicine, and is readily available to those employed in the care and management of horses. Such persons may take the drug indiscriminately, without medical supervision. We present a 33-year-old male race horse track worker who took phenylbutazone horse pills for a chronic toothache and subsequently suffered a major hemorrhage from a gastric ulcer. Human use of phenylbutazone horse pills should be considered by physicians confronted with patients who have upper gastrointestinal symptoms and gastric injury and who belong to this select group.
保泰松（PBZ）是一种非甾体抗炎药（NSAID），由于严重不良反应发生率高，通常不被处方使用。然而，它仍广泛用于马医学领域，从事马匹护理和管理工作的人员很容易获得。这些人可能在没有医疗监督的情况下随意服用该药物。我们报告了一名33岁的男性赛马场工作人员，他因慢性牙痛服用了保泰松马用丸剂，随后因胃溃疡大出血。面对有上消化道症状和胃损伤且属于这一特定群体的患者，医生应考虑到人类使用保泰松马用丸剂的情况。
