Asif Muhammad, Aslam Muhammad, Altaf Saima, Mustafa Sajid
Govt. College, Qadirpur Raan, Multan, Pakistan.
Department of Statistics, Bahauddin Zakariya University, Multan, Pakistan.
J Pediatr Endocrinol Metab. 2020 Jul 6. doi: 10.1515/jpem-2019-0527.
Objectives Children from different countries and with different ethnic backgrounds have a distinct pattern of central fat deposition. Therefore, it is essential to develop population-specific percentiles of waist circumference (WC), waist-to-height ratio (WHtR) and waist-to-height ratio exponent (WHtR (exp)) for the evaluation of central obesity. The objective of this study was to develop age-and-gender-specific smoothed WC and WHtR percentile curves for the Pakistani children and adolescents aged 2-18 years. Methods A cross-sectional data-set from a multi-ethnic anthropometric survey was considered. A sample of 10,668 healthy subjects (boys = 51.92%; and girls = 48.08%), aged 2-18 years was studied. Height (cm) and WC (cm) of each subject was measured under standard procedure and WHtR & WHtR (exp) were calculated. Age-and-gender-specific smoothed curves were obtained using the lambda-mu-sigma (LMS) method and compared with percentile curves obtained from different countries. Results Except few early ages, the WC values increased with age in both sexes. Both boys and girls had approximately similar WC during 6-11 years of age and after age of 11, the boys had larger WC than the girls had. For WHtR, the centile curves showed a continuous decrease by 16 years of age and then increased gradually. WHtR of the girls in various ages were having similar or higher than those of the boys. In comparison of WC 50th and 90th percentiles with other countries, it was found that except few ages, the Pakistani children had larger WC than the other reference populations and the results of WHtR were also comparable to the other nations. Conclusions We present new reference data of WC, WHtR and WHtR (exp) using a representative sample of the Pakistani children aged 2-18 years. These reference values can be used provisionally for early detection of central obesity and its associated risks in the Pakistani children.
目的 来自不同国家、具有不同种族背景的儿童有独特的中心性脂肪沉积模式。因此，制定针对特定人群的腰围（WC）、腰高比（WHtR）和腰高比指数（WHtR (exp)）百分位数对于评估中心性肥胖至关重要。本研究的目的是为2至18岁的巴基斯坦儿童和青少年制定年龄和性别特异性的平滑WC和WHtR百分位数曲线。方法 考虑来自多民族人体测量调查的横断面数据集。研究了10668名2至18岁的健康受试者样本（男孩 = 51.92%；女孩 = 48.08%）。按照标准程序测量每个受试者的身高（厘米）和WC（厘米），并计算WHtR和WHtR (exp)。使用lambda-mu-sigma（LMS）方法获得年龄和性别特异性的平滑曲线，并与来自不同国家的百分位数曲线进行比较。结果 除了少数早期年龄段外，WC值在两性中均随年龄增加。男孩和女孩在6至11岁期间的WC大致相似，11岁以后，男孩的WC大于女孩。对于WHtR，百分位数曲线在16岁之前持续下降，然后逐渐上升。各年龄段女孩的WHtR与男孩相似或更高。将WC第50和第90百分位数与其他国家进行比较时发现，除了少数年龄段外，巴基斯坦儿童的WC大于其他参考人群，并且WHtR的结果也与其他国家相当。结论 我们使用2至18岁巴基斯坦儿童的代表性样本提供了WC、WHtR和WHtR (exp)的新参考数据。这些参考值可临时用于早期检测巴基斯坦儿童的中心性肥胖及其相关风险。
