Trick G L, Nesher R, Cooper D G, Kolker A E, Bickler-Bluth M
Department of Ophthalmology, Washington University School of Medicine, St. Louis, Missouri.
Invest Ophthalmol Vis Sci. 1988 Oct;29(10):1486-91.
Both acquired color vision deficiencies and abnormal pattern electroretinograms (PERGs) are observed in patients with ocular hypertension (OHT) as well as in patients with glaucoma. In the present study we determined the prevalence of both of these functional deficits in a large group of OHT patients (N = 130). Color vision was tested with the desaturated D-15 and a color confusion score was used to quantitatively assess the magnitude of the color vision deficiency. Steady-state PERGs were evoked with rapidly alternating high contrast checkerboard patterns. Color vision deficits were detected in 23% of OHTs while 11.5% of the patients exhibited significant PERG amplitude reductions. Only 2.3% exhibited both abnormalities. The results suggest that although color vision deficiencies and PERG abnormalities are both evident in OHT, they are often dissociated findings.
眼压升高（OHT）患者和青光眼患者均存在后天性色觉缺陷和异常图形视网膜电图（PERG）。在本研究中，我们测定了一大组眼压升高患者（N = 130）中这两种功能缺陷的患病率。使用去饱和D - 15测试色觉，并使用颜色混淆评分定量评估色觉缺陷的程度。用快速交替的高对比度棋盘图案诱发稳态PERG。23%的眼压升高患者检测出色觉缺陷，而11.5%的患者表现出明显的PERG振幅降低。只有2.3%的患者同时表现出这两种异常。结果表明，尽管色觉缺陷和PERG异常在眼压升高患者中都很明显，但它们往往是分离的表现。
