Bampidis Vasileios, Azimonti Giovanna, de Lourdes Bastos Maria, Christensen Henrik, Dusemund Birgit, Kouba Maryline, Kos Durjava Mojca, López-Alonso Marta, López Puente Secundino, Marcon Francesca, Mayo Baltasar, Pechová Alena, Petkova Mariana, Sanz Yolanda, Villa Roberto Edoardo, Woutersen Ruud, Costa Lucio, Cubadda Francesco, Dierick Noël, Flachowsky Gerhard, Mantovani Alberto, Wallace Robert John, Tarres-Call Jordi, Ramos Fernando
EFSA J. 2019 May 2;17(5):e05697. doi: 10.2903/j.efsa.2019.5697. eCollection 2019 May.
Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on l-lysine monohydrochloride and concentrated liquid l-lysine (base) produced using KCCM 10227 when used as nutritional additives in feed and water for drinking for all animal species. The active substance is l-lysine. l-lysine HCl and concentrated liquid l-lysine (base) produced by the strain KCCM 10227 do not represent a risk for the target species, the consumer and the environment. l-lysine HCl produced by KCCM 10227 is hazardous by inhalation, it is not irritant to skin but mildly irritant to eyes and it is not a skin sensitiser. Concentrated liquid l-lysine (base) produced by KCCM 10227 is hazardous by inhalation, not irritant to skin and eyes and it is not a skin sensitiser. l-lysine HCl and concentrated liquid l-lysine (base) are considered as efficacious sources of the essential amino acid l-lysine for non-ruminant animal species. For the supplemental l-lysine to be as efficacious in ruminants as in non-ruminant species, it would require protection against degradation in the rumen.
应欧盟委员会的要求，动物饲料添加剂及产品或物质专家委员会（FEEDAP）被要求就使用KCCM 10227生产的L-赖氨酸盐酸盐和浓缩液L-赖氨酸（碱）作为所有动物物种饲料和饮用水中的营养添加剂给出科学意见。活性物质为L-赖氨酸。由KCCM 10227菌株生产的L-赖氨酸盐酸盐和浓缩液L-赖氨酸（碱）对目标物种、消费者和环境不构成风险。由KCCM 10227生产的L-赖氨酸盐酸盐吸入有害，对皮肤无刺激性，但对眼睛有轻度刺激性，且不是皮肤致敏剂。由KCCM 10227生产的浓缩液L-赖氨酸（碱）吸入有害，对皮肤和眼睛无刺激性，且不是皮肤致敏剂。L-赖氨酸盐酸盐和浓缩液L-赖氨酸（碱）被认为是非反刍动物必需氨基酸L-赖氨酸的有效来源。要使补充的赖氨酸在反刍动物中与在非反刍动物物种中一样有效，则需要防止其在瘤胃中降解。
