Bampidis Vasileios, Azimonti Giovanna, Bastos Maria de Lourdes, Christensen Henrik, Dusemund Birgit, Fašmon Durjava Mojca, Kouba Maryline, López-Alonso Marta, López Puente Secundino, Marcon Francesca, Mayo Baltasar, Pechová Alena, Petkova Mariana, Ramos Fernando, Sanz Yolanda, Villa Roberto Edoardo, Woutersen Ruud, Anguita Montserrat, Brozzi Rosella, Galobart Jaume, Pettenati Elisa, Tarrés-Call Jordi
EFSA J. 2021 Jul 23;19(7):e06706. doi: 10.2903/j.efsa.2021.6706. eCollection 2021 Jul.
Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of l-lysine sulfate produced by KCCM 80227 as a nutritional feed additive for all animal species. The FEEDAP Panel concluded that the production strain KCCM 80227 qualifies for the qualified presumption of safety (QPS) approach to safety assessment and is not detected in the final product. l-Lysine sulfate produced using KCCM 80227 does not pose any safety concern associated with the production strain. The additive under assessment is considered safe for the target species. When using l-lysine sulfate, the background sulfur/sulfate content in the compound feed should be taken into account. l-Lysine sulfate produced by KCCM 80227 is safe for the consumers, users and for the environment. The additive l-lysine sulfate is considered as an efficacious source of the essential amino acid l-lysine for non-ruminant animal species. For the supplemental l-lysine to be as efficacious in ruminants as in non-ruminant species, it would require protection against degradation in the rumen.
应欧盟委员会的要求，欧洲食品安全局（EFSA）被要求就KCCM 80227生产的L-赖氨酸硫酸盐作为所有动物物种的营养饲料添加剂的安全性和有效性发表科学意见。饲料添加剂和动物产品中微生物风险评估小组得出结论，生产菌株KCCM 80227符合安全评估的合格假定安全性（QPS）方法，且在最终产品中未检测到。使用KCCM 80227生产的L-赖氨酸硫酸盐不存在与生产菌株相关的任何安全问题。所评估的添加剂对目标物种被认为是安全的。使用L-赖氨酸硫酸盐时，应考虑配合饲料中的背景硫/硫酸盐含量。KCCM 80227生产的L-赖氨酸硫酸盐对消费者、使用者和环境都是安全的。添加剂L-赖氨酸硫酸盐被认为是反刍动物必需氨基酸L-赖氨酸的有效来源。为使补充的L-赖氨酸在反刍动物中与在非反刍动物物种中一样有效，需要防止其在瘤胃中降解。
