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污染物、食品接触材料、技术成分和营养风险领域的风险评估方法。

Risk assessment methodologies in the field of contaminants, food contact materials, technological ingredients and nutritional risks.

作者信息

Cătunescu Giorgiana M, Troncoso Ana Ma, Jos Angeles

出版信息

EFSA J. 2019 Sep 17;17(Suppl 2):e170911. doi: 10.2903/j.efsa.2019.e170911. eCollection 2019 Sep.

Abstract

The programme aimed at training the fellow in the risk assessment guidelines proposed by the EFSA in the field of contaminants, food contact materials, technological ingredients and nutritional risks. It had a modular 'learning by doing' approach and a balanced learning/case studies and theory. Module 1 offered an insight into chemical risk assessment and conferred transferable skills for a proper application of the framework. The hands-on activities consisted of three case studies that went from a simple exercise on an official opinion, to working in a team with experts to produce a new opinion, to an individual work to obtain a publishable review manuscript. Module 2 was a training in experimental toxicology designed to create a toxicological basis and to enable the fellow to perform toxicological studies for risk assessment purposes. She joined the team working on cyanotoxins, gained experience with both EFSA and Organization of Economic Cooperation and Development (OECD) guidelines on genotoxicity and an insight into the developing of analytical methods suitable for risk assessment purposes. During module 3, the fellow was trained in nutritional risk assessment and involved in experimental work in chemical characterisation, biomarkers and mechanisms of action of bioactive compounds. This developed the critical perspective when assessing nutritional and health claims related the design of experiments, methods used, interpretation of results and human relevance. Module 4 provided a 'hand-on experience' in scientific risk communication as the fellow was encouraged and supported in the participation at local, national and international workshops and congresses presenting the outcomes of the three modules. Thus, the fellow was successfully integrated in the day-by-day workflow of the department, gaining first-hand practical experience in risk assessment in a multicultural and interdisciplinary context. This enabled a productive exchange of good practices and contributed to building a European risk assessment community.

摘要

该项目旨在培训学员掌握欧洲食品安全局(EFSA)在污染物、食品接触材料、技术成分和营养风险领域提出的风险评估指南。它采用模块化的“边做边学”方法,学习、案例研究和理论之间保持平衡。模块1深入介绍了化学风险评估,并传授了正确应用该框架的可转移技能。实践活动包括三个案例研究,从基于官方意见的简单练习,到与专家团队合作得出新意见,再到独立完成一篇可发表的综述稿件。模块2是实验毒理学培训,旨在建立毒理学基础,使学员能够进行用于风险评估的毒理学研究。她加入了研究蓝藻毒素的团队,积累了有关EFSA和经济合作与发展组织(OECD)遗传毒性指南的经验,并深入了解了适用于风险评估目的的分析方法的开发。在模块3中,学员接受了营养风险评估培训,并参与了生物活性化合物的化学表征、生物标志物和作用机制方面的实验工作。这培养了在评估与实验设计、所用方法、结果解释和人体相关性相关的营养和健康声明时的批判性视角。模块4提供了科学风险沟通方面的“实践经验”,因为鼓励并支持学员参加地方、国家和国际研讨会及大会,展示三个模块的成果。因此,学员成功融入了部门的日常工作流程,在多元文化和跨学科背景下获得了风险评估的第一手实践经验。这促进了良好实践的有效交流,并有助于建立欧洲风险评估共同体。

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