Yu Meiping, Ye Zhenghao, Chen Yu, Qin Tingting, Kou Jiguang, Tian De'an, Xiao Fang
Department of Gastroenterology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Department of Biliary-Pancreatic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Aging (Albany NY). 2020 Jul 3;12(13):12468-12478. doi: 10.18632/aging.103525.
This study aimed to assess the disease conditions of patients with inflammatory bowel disease (IBD) in Hubei Province during the outbreak of Coronavirus Disease 2019 (COVID-19) by questionnaire online and guide their self-management during this epidemic.
A total of 102 eligible questionnaires were included. No patient we surveyed reported a diagnosis of COVID-19. Our result showed that 67.86% of patients with ulcerative colitis (UC) and 80.43% of patients with Crohn's disease (CD) were in remission, 85.29%of patients had a good quality of life. Part of the patients (21.57%) reported their disease conditions worsening. The reduction in physical exercise was a risk factor for worsening conditions (OR=17.593, p=0.009). Some patients reported an alteration of medication regimens during the epidemic.
The epidemic of COVID-19 might have a certain impact on many aspects of Hubei IBD patients within four weeks after the traffic control. Doctors could utilize the results from our questionnaire to guide IBD patients' self-management.
A questionnaire was designed containing the Harvey-Bradshaw Index (HBI), the 6-point Mayo Score, the short inflammatory bowel disease questionnaire (SIBDQ) and distributed to Hubei IBD patients online within four weeks of traffic control after the outbreak, it also included questions about patients' self-reported disease conditions and their epidemiological features of COVID-19.
本研究旨在通过在线问卷调查评估2019年冠状病毒病（COVID-19）疫情期间湖北省炎症性肠病（IBD）患者的疾病状况，并指导他们在疫情期间进行自我管理。
共纳入102份合格问卷。我们调查的患者中无人报告诊断为COVID-19。结果显示，67.86%的溃疡性结肠炎（UC）患者和80.43%的克罗恩病（CD）患者处于缓解期，85.29%的患者生活质量良好。部分患者（21.57%）报告病情恶化。体育锻炼减少是病情恶化的一个危险因素（OR=17.593，p=0.009）。一些患者报告在疫情期间改变了用药方案。
COVID-19疫情可能在交通管制后的四周内对湖北IBD患者的多个方面产生一定影响。医生可利用我们问卷的结果指导IBD患者的自我管理。
设计了一份包含哈维-布拉德肖指数（HBI）、6分制梅奥评分、简短炎症性肠病问卷（SIBDQ）的问卷，并在疫情爆发后交通管制的四周内在线分发给湖北IBD患者，问卷还包括患者自我报告的疾病状况以及他们的COVID-19流行病学特征相关问题。
