Wang Min, Liu Guoliang, Mu Yu, He Hongyu, Wang Shuang, Li Jiannan
Department of General Surgery.
Operating Theater and Department of Anesthesiology.
Medicine (Baltimore). 2020 Jul 2;99(27):e20941. doi: 10.1097/MD.0000000000020941.
Tailgut cyst (TGC) is a rare congenital disease that originates from residues of the tail intestine during the embryonic period. Most TGCs are benign lesions and the malignant transition is very rare.
A 50-year-old woman attended our department complaining of defecation difficulty for more than 2 months. She reported irregular defecation with a small amount of liquid stool, 3 to 4 times per day.
Biochemical analysis showed high levels of carcinoembryonic antigen (79.89 ng/mL; normal, 0-3 ng/mL) and carbohydrate antigen 199 (57.60 U/mL; normal, 0-35 U/mL). Abdominal computer tomography and magnetic resonance imaging showed a large cystic mass with enhanced signals. Post-surgical histopathology indicated that the mass was a TGC with adenocarcinoma transition.
The cyst was completely resected. Symptomatic treatment was further performed, and the patient recovered well.
We reported a rare case of a large TGC with adenocarcinoma transition. CT, MRI, and histopathology are important to diagnose TGC. Complete surgical resection is the first choice to treat TGC.
尾肠囊肿(TGC)是一种罕见的先天性疾病,起源于胚胎期尾肠的残留物。大多数TGC是良性病变,恶变非常罕见。
一名50岁女性因排便困难2个多月前来我院就诊。她报告排便不规律,每天有少量稀便3至4次。
生化分析显示癌胚抗原水平升高(79.89 ng/mL;正常范围0 - 3 ng/mL)和糖类抗原199升高(57.60 U/mL;正常范围0 - 35 U/mL)。腹部计算机断层扫描和磁共振成像显示一个大的囊性肿块,信号增强。术后组织病理学表明该肿块是一个发生腺癌转变的TGC。
囊肿被完全切除。进一步进行了对症治疗,患者恢复良好。
我们报告了一例罕见的发生腺癌转变的巨大TGC病例。CT、MRI和组织病理学对诊断TGC很重要。完整的手术切除是治疗TGC的首选方法。