Li Ya-Ming, Xu Jian-Hua, Zhao Yan-Xin
Department of Neurology, Jiading District Central Hospital affiliated to Shanghai University of Medicine & Health Sciences.
Department of Neurology, Tenth People's Hospital affiliated to Tongji University, Shanghai, China.
Medicine (Baltimore). 2020 Jul 2;99(27):e20952. doi: 10.1097/MD.0000000000020952.
Patients with stroke have a high risk of infection which may be predicted by age, procalcitonin, interleukin-6, C-reactive protein, National Institute of Health stroke scale (NHSS) score, diabetes, etc. These prediction methods can reduce unfavourable outcome by preventing the occurrence of infection.We aim to identify early predictors for urinary tract infection in patients after stroke.In 186 collected acute stroke patients, we divided them into urinary tract infection group, other infection type groups, and non-infected group. Data were recorded at admission. Independent risk factors and infection prediction model were determined using Logistic regression analyses. Likelihood ratio test was used to detect the prediction effect of the model. Receiver operating characteristic curve and the corresponding area under the curve were used to measure the predictive accuracy of indicators for urinary tract infection.Of the 186 subjects, there were 35 cases of urinary tract infection. Elevated interleukin-6, higher NIHSS, and decreased hemoglobin may be used to predict urinary tract infection. And the predictive model for urinary tract infection (including sex, NIHSS, interleukin-6, and hemoglobin) have the best predictive effect.This study is the first to discover that decreased hemoglobin at admission may predict urinary tract infection. The prediction model shows the best accuracy.
中风患者具有较高的感染风险,年龄、降钙素原、白细胞介素-6、C反应蛋白、美国国立卫生研究院卒中量表(NHSS)评分、糖尿病等因素可能对其具有预测作用。这些预测方法可通过预防感染的发生来减少不良后果。我们旨在确定中风后患者尿路感染的早期预测因素。在收集的186例急性中风患者中,我们将他们分为尿路感染组、其他感染类型组和未感染组。在入院时记录数据。使用逻辑回归分析确定独立危险因素和感染预测模型。采用似然比检验检测模型的预测效果。采用受试者工作特征曲线及其相应的曲线下面积来衡量尿路感染指标的预测准确性。在186名受试者中,有35例发生尿路感染。白细胞介素-6升高、NIHSS评分较高以及血红蛋白降低可能用于预测尿路感染。并且尿路感染的预测模型(包括性别、NIHSS、白细胞介素-6和血红蛋白)具有最佳预测效果。本研究首次发现入院时血红蛋白降低可能预测尿路感染。该预测模型显示出最佳准确性。