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关节内注射在治疗无减压的椎间盘移位后果中的应用。

The Application of Intra-Articulr Injections for Management of the Consequences of Disc Displacement without Reduction.

机构信息

Prosthodontics Department, Consulting Room of Temporomandibular Disorders, Jagiellonian University, Medical College, 4 Montelupich Str., 31-155 Krakow, Poland.

出版信息

Int J Environ Res Public Health. 2020 Jul 1;17(13):4726. doi: 10.3390/ijerph17134726.

Abstract

The aim of the study was to make a comparative studies on the effectiveness of platelet rich plasma (PRP) and hyaluronic acid (HA) in intra-articular injections to the temporomandibular joints-in double blind studies application-based on the analysis of selected clinical parameters of functional efficiency and the mean value of joint's pain intensity before and after management. The study enrolled a group of 100 patients, aged 21 to 43 years, of both sexes, who came for the prosthodontic treatment. All patients had II b group of disorder according to the Research Diagnostic Criteria/Temporomandibular Disorder, and were consecutively, alternately assigned to the groups, 50 patients in each. Study group PRP was treated with intra-articular injection of platelet rich plasma and study group HA had injection with hyaluronic acid. The examination was double-blind, so that the injecting physician and the patient were not informed what kind of medicinal substance they received in the joint injection. The final selected clinical parameters did not differ statistically significantly between the groups, what means that both administered substances were effective in the repair of intra-articular structures. The results of research showed that the use of PRP and HA in intraarticular joint's injections positively affects in selected clinical parameters and decrease of the pain in temporomandibular joints in the case of disc displacement without reduction.

摘要

本研究旨在通过分析选择的功能效率临床参数和管理前后关节疼痛强度均值,对富血小板血浆(PRP)和透明质酸(HA)在颞下颌关节内注射中的有效性进行对比研究——基于双盲研究应用。该研究纳入了 100 名年龄在 21 至 43 岁之间的患者,性别不限,他们均因修复治疗而来就诊。所有患者均符合 Research Diagnostic Criteria/Temporomandibular Disorder 的 II b 组障碍,并连续交替分为两组,每组 50 名患者。研究组 PRP 采用富含血小板的关节内注射治疗,研究组 HA 采用透明质酸注射治疗。检查是双盲的,因此注射医生和患者都不知道他们在关节注射中接受了哪种药物。最终选择的临床参数在两组之间没有统计学上的显著差异,这意味着两种给药物质在修复关节内结构方面都有效。研究结果表明,PRP 和 HA 在关节内注射中的应用对选择的临床参数有积极影响,并可减轻无复位关节盘移位的颞下颌关节疼痛。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48b9/7370078/92f8666d61e9/ijerph-17-04726-g001.jpg

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