Yang John Zhiyong, Dokpuang Dech, Nemati Reza, He Kevin Haokun, Zheng Andy Baige, Petrov Maxim S, Lu Jun
School of Science, Faculty of Health and Environmental Sciences, Auckland University of Technology, Auckland 1010, New Zealand.
Division of Medical Technology, School of Allied Health Sciences, University of Phayao, Phayao 56000, Thailand.
Biomedicines. 2020 Jun 25;8(6):174. doi: 10.3390/biomedicines8060174.
Anthropometric indices, such as body mass index (BMI), waist circumference (WC), and waist to height ratio (WHtR), have limitations in accurately predicting the pathophysiology of diabetes mellitus, cardiovascular diseases, and metabolic syndrome due to ethnic differences in fat distribution. Recent studies showed that the visceral adipose tissue (VAT) deposition and fat content of internal organs, most notably intra-hepatic and intra-pancreatic fat, has emerged as a more important parameter. In this study, we aimed to assess the coordination between the traditional anthropometric indices and the various fat depositions within different ethnicities in New Zealand. We recruited 104 participants with different ethnic backgrounds, including New Zealand Europeans, Māori (the indigenous people of New Zealand), Pacific Islanders (PI), and Asians. Their weight, height, and WC were measured, and subcutaneous, visceral, intra-hepatic, and intra-pancreatic fat depositions were obtained by magnetic resonance imaging (MRI). The result showed VAT, but not subcutaneous adipose tissue (SAT) depositions at all levels were significantly varied among the three groups. BMI was associated best with L23SAT in NZ Europeans (30%) and L45VAT in Māori/PI (24.3%). WC and WHtR were correlated well with L45SAT in the total population (18.8% and 12.2%, respectively). Intra-pancreatic fat deposition had a positive Pearson relationship with NZ European BMI and Māori/PI WC, but no regression correlation with anthropometric indices. Conventional anthropometric indices did not correspond to the same fat depositions across different ethnic groups.
由于脂肪分布存在种族差异，诸如体重指数（BMI）、腰围（WC）和腰高比（WHtR）等人体测量指标在准确预测糖尿病、心血管疾病和代谢综合征的病理生理方面存在局限性。最近的研究表明，内脏脂肪组织（VAT）沉积以及内脏器官的脂肪含量，尤其是肝内和胰腺内脂肪，已成为一个更为重要的参数。在本研究中，我们旨在评估新西兰不同种族中传统人体测量指标与各种脂肪沉积之间的协调性。我们招募了104名具有不同种族背景的参与者，包括新西兰欧洲人、毛利人（新西兰原住民）、太平洋岛民（PI）和亚洲人。测量了他们的体重、身高和腰围，并通过磁共振成像（MRI）获得了皮下、内脏、肝内和胰腺内的脂肪沉积情况。结果显示，三组之间所有水平的VAT存在显著差异，但皮下脂肪组织（SAT）沉积无显著差异。在新西兰欧洲人中，BMI与L23SAT的相关性最佳（30%），在毛利人/太平洋岛民中与L45VAT的相关性最佳（24.3%）。在总人群中，WC和WHtR与L45SAT的相关性良好（分别为18.8%和12.2%）。胰腺内脂肪沉积与新西兰欧洲人的BMI以及毛利人/太平洋岛民的WC呈正皮尔逊关系，但与人体测量指标无回归相关性。传统人体测量指标在不同种族群体中与相同的脂肪沉积并不对应。
