Wu Hong-yan, Xu Shuang-ying, Chen Lu-lu, Zhang Hui-fang
Department of Endocrinology, Union Hospital, Tongji Medical School, Huazhong Technology University, Wuhan 430022, People's Republic of China.
Chin J Physiol. 2009 Dec 31;52(6):441-5. doi: 10.4077/cjp.2009.amh064.
The accumulation of fat in visceral (VA) and subcutaneous abdominal adipose tissue (SA) is highly correlated with the metabolic abnormalities that contribute to increased risk of diabetes mellitus and cardiovascular disease. The purpose of the study was to determine which of the four indices-waist circumference (WC), waist-to-hip ratio (WHR), waist to height ratio (WHtR) and body mass index (BMI)-was the best predictor of VA and SA in men. We studied 111 men with a wide range of BMI, WC, WHtR, WHR and BMI determined by standard methods. SA and VA were quantified using computed tomography. In univariate and multiple regression analyses, WHtR had the highest correlation with VA and SA. To assess the relative strength of these associations, we used non-nested regression models. WHtR was a stronger predictor of SA than BMI (P = 0.02), but the relative strength of WC and BMI in predicting SA did not differ significantly (P > 0.05). WHtR was a stronger predictor of VA than WC (P = 0.012), BMI (P < 0.001) or WHR (P < 0.001). In men, WHtR is a good anthropometric index which has a stronger correlation with the distribution of visceral and subcutaneous abdominal adipose tissue than BMI or WHR. Its association is closer to or stronger than WC.
内脏（VA）和腹部皮下脂肪组织（SA）中的脂肪堆积与导致糖尿病和心血管疾病风险增加的代谢异常高度相关。本研究的目的是确定腰围（WC）、腰臀比（WHR）、腰高比（WHtR）和体重指数（BMI）这四个指标中哪一个是男性VA和SA的最佳预测指标。我们研究了111名男性，他们的BMI、WC、WHtR、WHR范围广泛，且通过标准方法测定了BMI。使用计算机断层扫描对SA和VA进行量化。在单变量和多变量回归分析中，WHtR与VA和SA的相关性最高。为了评估这些关联的相对强度，我们使用了非嵌套回归模型。WHtR是SA比BMI更强的预测指标（P = 0.02），但WC和BMI在预测SA方面的相对强度没有显著差异（P > 0.05）。WHtR是VA比WC（P = 0.012）、BMI（P < 0.001）或WHR（P < 0.001）更强的预测指标。在男性中，WHtR是一个良好的人体测量指标，与内脏和腹部皮下脂肪组织分布的相关性比BMI或WHR更强。其关联比WC更紧密或更强。
