Han Song Hyun, Kim Soon Heum, Kim Cheol Keun, Jo Dong In
Department of Plastic and Reconstructive Surgery, Konkuk University Chungju Hospital, Konkuk University School of Medicine, Chungju, Korea.
Arch Craniofac Surg. 2020 Jun;21(3):188-192. doi: 10.7181/acfs.2020.00073. Epub 2020 Jun 29.
The most common forms of nonmelanocytic skin cancer (NMSC) are basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The growing incidence of skin cancer in the Republic of Korea has sparked increasing scientific interest in these types of tumors. In the case described herein, multiple NMSCs occurred asynchronously in various areas of the body in a single patient. A 67-year-old man presented with an ulcerative lesion on the right retro-auricle and multiple keratinized masses on the back and face. The right retro-auricular lesion was diagnosed as BCC, and the keratinized masses on the patient's back and face were diagnosed as SCC. He subsequently presented with numerous pigmented skin lesions on the forehead, temple, pre-auricle, neck, right forearm, right hand, and both thighs. One lesion on the neck was diagnosed as BCC, and five lesions on the right hand and forearm were diagnosed as SCC. The patient was also diagnosed with supraglottic SCC and external auditory canal SCC. An otolaryngologist performed radical excision of the primary SCC. Suspected skin cancer lesions observed on the face and both ears were diagnosed as SCC. Patients with multiple NMSCs are at an elevated risk for additional skin cancers, making periodic follow-up important; furthermore, all suspicious lesions should be biopsied.
非黑素细胞性皮肤癌（NMSC）最常见的形式是基底细胞癌（BCC）和鳞状细胞癌（SCC）。韩国皮肤癌发病率的不断上升引发了对这类肿瘤越来越多的科学关注。在本文所述病例中，一名患者身体不同部位异步出现了多发性NMSC。一名67岁男性患者，右侧耳后出现溃疡性病变，背部和面部有多个角化肿物。右侧耳后病变被诊断为基底细胞癌，患者背部和面部的角化肿物被诊断为鳞状细胞癌。随后，他的前额、颞部、耳前、颈部、右前臂、右手和双大腿出现了大量色素沉着性皮肤病变。颈部的一个病变被诊断为基底细胞癌，右手和右前臂的五个病变被诊断为鳞状细胞癌。该患者还被诊断为声门上鳞状细胞癌和外耳道鳞状细胞癌。一名耳鼻喉科医生对原发性鳞状细胞癌进行了根治性切除。面部和双耳观察到的疑似皮肤癌病变被诊断为鳞状细胞癌。患有多发性NMSC的患者发生其他皮肤癌的风险升高，因此定期随访很重要；此外，所有可疑病变都应进行活检。
