Department of Environment and Health, Istituto Superiore di Sanità, Rome (Italy);
Department of Health Services and Epidemiological Observatory, Regional Health Authority, Sicilian Region, Palermo (Italy).
Epidemiol Prev. 2020 Mar-Jun;44(2-3):137-144. doi: 10.19191/EP20.2-3.P137.036.
to analyse the asbestos-related diseases risk among the former workers of Sacelit asbestos-cement plant, operating in San Filippo del Mela (Sicily: 1958- 1993).
cohort study.
228 subjects were employed in Sacelit from 1958 to 1993. Due to the available observation periods, the analyses of the different outcomes were performed for the subjects alive at the beginning of the respective follow up periods: mortality (1986-2018) was analysed for 204 subjects (177 men, 27 women), hospitalization (2001-2016) for 164 workers (139 men, 25 women) and the incidence of mesothelioma (1998-2016) was estimated for 178 subjects (153 men, 25 women).
mortality (Standardized Mortality Ratio: SMR) and hospitalization (Standardized Hospitalization Ratio: SHR) from specific diseases were analysed. Incidence (Standardized Incidence Ratio: SIR) of mesothelioma cases was detected, also. SMR (1986-2014), SHR (2001-2016) and SIR (1998-2016), with 95% Confidence Intervals, were computed with respect to the regional rates, with STATA11.
in the men cohort, mortality from lung (17 cases, SMR 2.83) and pleural cancers (5 cases, SMR 30) and from asbestosis (15 cases, SMR 1,930) was in excess. The risk of hospitalization was in excess, in both genders, from lung cancer (men: 6 cases, SHR 4.1; women: 2 cases, SHR 8.6) and asbestosis (men: 17 cases, SHR 1,304; women: 6 cases, SHR 2,455). The incidence of mesothelioma was in excess in men (5 cases, SIR 23.9); no female cases of mesothelioma were observed.
a high occurrence of asbestos-related diseases in the cohort, particularly among men, was observed. The excess of hospitalization from asbestosis and lung cancer was highlighted also in women. The prosecution of the on-going health surveillance plan is particularly appropriated.
分析 Sacelit 石棉水泥厂前工人的石棉相关疾病风险，该工厂位于西西里岛的圣菲利波德尔梅拉（San Filippo del Mela）（1958-1993 年）。
队列研究。
1958 年至 1993 年期间，共有 228 名员工在 Sacelit 工作。由于可观察的观察期，对不同结果的分析是针对各自随访期开始时存活的受试者进行的：死亡率（1986-2018 年）分析了 204 名受试者（177 名男性，27 名女性），住院率（2001-2016 年）分析了 164 名工人（139 名男性，25 名女性），而间皮瘤（1998-2016 年）的发病率估计为 178 名受试者（153 名男性，25 名女性）。
分析了特定疾病的死亡率（标准化死亡率比：SMR）和住院率（标准化住院率比：SHR）。还检测了间皮瘤病例的发病率（标准化发病率比：SIR）。使用 STATA11，根据区域发病率计算了男性队列的死亡率（1986-2014 年）、住院率（2001-2016 年）和发病率（1998-2016 年），并计算了 95%置信区间。
在男性队列中，死于肺癌（17 例，SMR 2.83）和胸膜癌（5 例，SMR 30）以及石棉沉着病（15 例，SMR 1930）的人数过多。两性的肺癌（男性：6 例，SHR 4.1；女性：2 例，SHR 8.6）和石棉沉着病（男性：17 例，SHR 1304；女性：6 例，SHR 2455）住院风险过高。男性间皮瘤的发病率过高（5 例，SIR 23.9）；未观察到女性间皮瘤病例。
该队列中观察到石棉相关疾病的发生率很高，特别是在男性中。在女性中，石棉沉着病和肺癌的住院人数过多也很突出。特别适合继续进行正在进行的健康监测计划。
