Chanda Bwalya Mpelwa, Chen Xiao-Qing
Department of Pediatrics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Department of Pediatrics, First Affiliation Hospital of Nanjing Medical University, Nanjing, China.
Front Pediatr. 2023 Jun 5;11:1120763. doi: 10.3389/fped.2023.1120763. eCollection 2023.
The coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused many significant changes to all aspects of day to day life. The disease has spread and reached pandemic proportions. The principle route of transmission is the respiratory route. Infants, pregnant women and breastfeeding mothers have all been affected. Many interventions and guidelines from important societies have been instituted in order to curb the transmission of the disease. These have involved both pharmacological and non-pharmacological methods. COVID-19 vaccines have also emerged as important methods of primary prevention of the disease. But several questions have been raised concerning the safety and efficacy of their use in pregnant and breastfeeding mothers. It has also not been clear if the vaccines are effective in generating a robust immune response in the pregnant women and breastfeeding mothers to confer passive immunity to the fetuses and infants, respectively. And they have not been tested in infants. The aspect of infant feeding has equally been affected. Although breast milk has not been known to serve as the vehicle of transmission of the virus, there is still some lack of uniformity of practice regarding breastfeeding when a mother has SARS-CoV-2 infection. This has led to infant feeding being done by the use of commercial formula feeds, pasteurized human donor breast milk, feeding on the mother's own expressed breast milk by a care giver and directly breastfeeding with skin to skin contact. This is despite breast milk being the most physiologically appropriate type of feed for infants. Therefore the pertinent question remains; should breastfeeding continue during the pandemic continue? This review also seeks to analyse the vast amount of scientific information regarding the subject and to synthesize science-based information.
由严重急性呼吸综合征冠状病毒2(SARS-CoV-2)引起的2019冠状病毒病(COVID-19)给日常生活的方方面面带来了许多重大变化。该疾病已经传播并达到了大流行的程度。主要传播途径是呼吸道途径。婴儿、孕妇和哺乳期母亲都受到了影响。为了遏制疾病的传播,重要协会制定了许多干预措施和指南。这些措施包括药理学和非药理学方法。COVID-19疫苗也已成为预防该疾病的重要一级预防方法。但对于在孕妇和哺乳期母亲中使用疫苗的安全性和有效性提出了几个问题。疫苗是否能在孕妇和哺乳期母亲中有效产生强大的免疫反应,分别为胎儿和婴儿提供被动免疫也尚不清楚。而且它们尚未在婴儿中进行测试。婴儿喂养方面同样受到了影响。尽管母乳尚未被认为是病毒传播的载体,但当母亲感染SARS-CoV-2时,在母乳喂养方面仍存在一些做法不统一的情况。这导致婴儿喂养采用商业配方奶、巴氏消毒的人捐赠母乳、护理人员用母亲自己挤出的母乳喂养以及直接皮肤接触母乳喂养。尽管母乳是对婴儿生理上最合适的喂养方式。因此,相关问题仍然存在;在大流行期间母乳喂养是否应该继续?本综述还旨在分析有关该主题的大量科学信息,并综合基于科学的信息。