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使用卡比马唑和碘化钾准备手术的Graves病患者甲状腺与外周静脉血中促甲状腺素受体抗体梯度及T细胞亚群分布的缺失

Absence of gradient of thyrotropin receptor antibody and T cell subset distribution between thyroid and peripheral venous blood in patients with Graves' disease prepared for surgery with carbimazole and potassium iodide.

作者信息

Wilson R, McKillop J H, Pearson C, Burnett A K, Gunn I, McNicol A M, Thomson J A

机构信息

University Department of Medicine, Royal Infirmary, Glasgow, UK.

出版信息

Clin Exp Immunol. 1988 Aug;73(2):265-8.

Abstract

The aim of the study was to examine tri-iodothyronine, thyroxine, thyroid antibody and thyrotropin receptor antibody levels in thyroid and peripheral venous blood at the time of surgery in patients with Graves' disease. T cell subset patterns in peripheral and thyroidal venous blood were compared to the distribution of T cell subset patterns within the thyroid gland itself. The results showed that at the time of surgery there were no significant differences in any of the parameters measured between thyroidal and peripheral venous samples. T cell subset patterns within the thyroid gland were subjectively similar to those in the venous samples.

摘要

本研究的目的是检测格雷夫斯病患者手术时甲状腺及外周静脉血中的三碘甲状腺原氨酸、甲状腺素、甲状腺抗体和促甲状腺素受体抗体水平。将外周和甲状腺静脉血中的T细胞亚群模式与甲状腺腺体内T细胞亚群模式的分布进行比较。结果显示,手术时甲状腺静脉样本和外周静脉样本之间所测的任何参数均无显著差异。甲状腺腺体内的T细胞亚群模式在主观上与静脉样本中的相似。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/364e/1541615/683c705e28b6/clinexpimmunol00095-0105-a.jpg

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