健康眼后极形态的眼轴相关个体间变异性。
Axial length-related inter-individual variability in the posterior pole morphology of healthy eyes.
机构信息
Department of Ophthalmology, University of Padova, Street Giustiniani n. 2 35128, Padova, Italy.
Department of Ophthalmology of Orlandi Hospital, Bussolengo, Verona, Italy.
出版信息
Int Ophthalmol. 2020 Nov;40(11):2901-2911. doi: 10.1007/s10792-020-01474-6. Epub 2020 Jul 6.
AIM
To evaluate morphological characteristics of optic nerve head (ONH) and fovea (F) related to axial length (AL) in healthy eyes.
METHODS
This is an observational study. A consecutive series of healthy subjects was enrolled. Demographic and clinical parameters were age, gender, eye, intraocular pressure, spherical equivalent, AL. Tomographic parameters were ONH-F distance, ONH-F angle, horizontal and vertical ONH diameters, retinal nerve fiber layer (RNFL) thickness and foveal profile patterns.
RESULTS
One hundred six eyes (56 patients) were recruited. A correlation between AL and ONH-F distance was demonstrated (p = 0.0342). Horizontal diameter decreased with increasing AL (p = 0.0003), conferring to ONH a more oval shape. A significant decrease in RNFL thickness was correlated with AL, except for temporal quadrant. Two foveal profile patterns were described: concave and straight patterns. Eyes with concave pattern were longer than eyes with straight pattern.
CONCLUSION
Eye elongation affects the morphology of the ONH, the fovea and the distribution of retinal nerve fibers.
目的
评估健康眼视神经乳头（ONH）和黄斑（F）与眼轴长度（AL）相关的形态特征。
方法
这是一项观察性研究。连续纳入了一系列健康受试者。人口统计学和临床参数包括年龄、性别、眼别、眼压、球镜等效、AL。断层参数包括视神经乳头-F 距离、视神经乳头-F 角度、水平和垂直视神经乳头直径、视网膜神经纤维层（RNFL）厚度和黄斑形态。
结果
共纳入 106 只眼（56 例患者）。AL 与视神经乳头-F 距离呈正相关（p=0.0342）。水平直径随 AL 的增加而减小（p=0.0003），使视神经乳头呈更椭圆形。除颞象限外，RNFL 厚度与 AL 呈显著负相关。描述了两种黄斑形态：凹形和直线形。具有凹形形态的眼比具有直线形形态的眼更长。
结论
眼球伸长会影响视神经乳头、黄斑和视网膜神经纤维的分布的形态。
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