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法国感染严重急性呼吸综合征冠状病毒 2 的孕妇回顾性描述。

Retrospective Description of Pregnant Women Infected with Severe Acute Respiratory Syndrome Coronavirus 2, France.

出版信息

Emerg Infect Dis. 2020 Sep;26(9):2069-2076. doi: 10.3201/eid2609.202144. Epub 2020 Jul 6.

DOI:10.3201/eid2609.202144
PMID:32633712
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7454086/
Abstract

Fix data are available on the management of pregnant women infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We conducted a retrospective study of 100 pregnant women with SARS-CoV-2 infection in 4 obstetric units in the Paris metropolitan area of France during March 12-April 13, 2020. Among patients, 52 (52%) were hospitalized, 10 (10%) in intensive care units (ICUs). Women with higher body mass indexes (BMIs; median 30.7 kg/m) were more likely to be hospitalized in ICUs than other women (median BMI 26.2 kg/m). Women hospitalized in ICUs had lower lymphocyte count at diagnosis (median 0.77 × 10 cells/L) than women not hospitalized in ICUs (median lymphocyte count 1.15 × 10 cells/L). All women requiring oxygen >5 L/min were intubated. Clinical and laboratory evaluation of SARS-CoV-2-positive pregnant women at the time of diagnosis can identify patients at risk for ICU hospitalization.

摘要

有关严重急性呼吸综合征冠状病毒 2(SARS-CoV-2)感染孕妇管理的数据已经可用。我们对 2020 年 3 月 12 日至 4 月 13 日期间法国巴黎大都市区的 4 个产科单位的 100 名 SARS-CoV-2 感染孕妇进行了回顾性研究。在患者中,有 52 名(52%)住院,10 名(10%)住进重症监护病房(ICU)。体重指数(BMI)较高的女性(中位数 30.7kg/m)比其他女性更有可能住进 ICU(中位数 BMI 26.2kg/m)。住进 ICU 的女性在诊断时的淋巴细胞计数较低(中位数 0.77×10 个细胞/L),而未住进 ICU 的女性的淋巴细胞计数中位数为 1.15×10 个细胞/L。所有需要 5L/min 以上氧气的女性均被插管。在诊断时对 SARS-CoV-2 阳性孕妇进行临床和实验室评估,可以识别出有住进 ICU 风险的患者。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e7c/7454086/f3d9390efe98/20-2144-F.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e7c/7454086/f3d9390efe98/20-2144-F.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e7c/7454086/f3d9390efe98/20-2144-F.jpg

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