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巴西与 COVID-19 相关的孕妇和产后妇女的临床、流行病学特征和死亡率:队列研究。

Clinical, epidemiological characteristics and mortality of pregnant and postpartum women associated with COVID-19 in Brazil: cohort study.

机构信息

Faculdade de Enfermagem Universidade Santo Amaro São PauloSP Brazil Faculdade de Enfermagem, Universidade Santo Amaro, São Paulo, SP, Brazil.

Escola de Enfermagem de Ribeirão Preto Universidade de São Paulo Ribeirão PretoSP Brazil Escola de Enfermagem de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brazil.

出版信息

Rev Bras Ginecol Obstet. 2024 Jun 27;46. doi: 10.61622/rbgo/2024rbgo52. eCollection 2024.

Abstract

OBJECTIVE

To analyze the death of Brazilian pregnant and postpartum women due to COVID-19 or unspecific cause.

METHODS

This is retrospective, descriptive-exploratory, population-based study carried out with the Sistema de Informação de Vigilância Epidemiológica da Gripe (SIVEP-Gripe) database, with pregnant and postpartum women of reproductive age who died from confirmed COVID-19 between 2020 and 2021. The chosen variables were: age, gestational period, type and number of comorbidities, skin color, using the statistical software R Foundation for Statistical Computing Platform, version 4.0.3 and Statistical Package for Social Science, version 29.0 for analysis.

RESULTS

A total of 19,333 cases of pregnant and postpartum women aged between 10 and 55 years diagnosed with SARS were identified, whether due to confirmed COVID-19 or unspecific causes. Of these, 1,279 died, these cases were classified into two groups according to the cause of death: deaths from COVID-19 (n= 1,026) and deaths from SARS of unspecific cause (n= 253).

CONCLUSION

The risk of death increased among black and brown women, in the postpartum period and with the presence of comorbidities, mainly diabetes, cardiovascular diseases and obesity. The data presented here draw attention to the number of deaths from SARS, especially among sociodemographic profiles, precarious access to health, such as the black population. In addition, limitations in adequate access to health care are reinforced by even lower rates of ICU admissions among women who died from SARS of an unspecified cause.

摘要

目的

分析因 COVID-19 或非特异性原因导致巴西妊娠和产后妇女死亡的情况。

方法

这是一项回顾性、描述性-探索性、基于人群的研究,使用了 Síndromes Respiratórios Agudos Grave (SIVEP-Gripe) 数据库,纳入了 2020 年至 2021 年间因确诊 COVID-19 而死亡的 10 至 55 岁有生育能力的妊娠和产后妇女。选择的变量包括年龄、妊娠周期、合并症的类型和数量、肤色,并使用 R Foundation for Statistical Computing Platform 版本 4.0.3 和 Statistical Package for Social Science 版本 29.0 进行分析。

结果

共确定了 19333 例年龄在 10 至 55 岁之间的妊娠和产后妇女患有 SARS,这些妇女因确诊 COVID-19 或非特异性原因而被诊断。其中 1279 人死亡,这些病例根据死因分为两组:COVID-19 死亡(n=1026)和非特异性 SARS 死亡(n=253)。

结论

黑人女性和棕色人种女性、产后女性和合并症患者(主要是糖尿病、心血管疾病和肥胖)的死亡风险增加。这里呈现的数据提请注意 SARS 导致的死亡人数,尤其是在社会人口统计学特征、卫生保健获取机会不平等的情况下,例如黑人。此外,甚至 ICU 收治率较低,进一步加剧了非特异性 SARS 死亡女性的卫生保健获取不足的问题。

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