Laboratory of Genetics and Biometry, Department of Biology, Faculty of Sciences, Ibn Tofail University, Kenitra.
Afr J Prim Health Care Fam Med. 2020 Jun 15;12(1):e1-e6. doi: 10.4102/phcfm.v12i1.2195.
Background: In Morocco, and many other African countries, there is a paucity of antihypertensive and antidiabetics use amongst the general population.
To investigate the epidemiological profile of antihypertensive and antidiabetics use and analysis their adverse reactions.
This study was conducted in the prefecture of Figuig, Morocco.
A cross-sectional descriptive study. Data was collected using semi-structured questionnaire about their pharmacological treatment and presented using descriptive statistical analysis.
Sample of 244 subjects, predominantly women 58.15% (p 0.03) composed of diabetic patients 56.96% (n = 139) and hypertensive patients 43.03% (n = 105). After adjustments, 60.24% of all patients were under monotherapy. The diabetics were being treated using the Biguanide class (26.92%), insulin (20.0%) and sulfonylureas (10.0%) while hypertensive patients were treated by Calcium Channel Blockers (27.36%), Angiotensin Converting Enzyme Inhibitors (21.05%), Angiotensin T-Blockers (16.84%), Diuretics (7.36%) and β-adrenergic receptors blockers (3.15%). In total, 23.00% of all subjects have experienced negative side-effects, mostly, reported (90.38%) to health professionals and 23.52% of them have interrupted temporarily or try to change their treatment. Gastro-intestinal problems were the most adverse reactions reported (11.11%) followed by headache, dizziness and tinnitus (6.66%) and asthenia, feeling sick and feeling of faintness (5.33%).
Managing diabetes and hypertension entails a lot of public challenges and requires more focus and interest, especially amongst the illiterate population in remote areas. Some of the suggested ways to help face the problem include the introduction of new innovative measures, systems of fellow-up and adverse reactions.
在摩洛哥和许多其他非洲国家,普通人群中抗高血压药和抗糖尿病药物的使用率很低。
调查抗高血压药和抗糖尿病药物的使用情况,并分析其不良反应。
本研究在摩洛哥菲古格省进行。
采用横断面描述性研究。使用半结构化问卷收集关于他们的药物治疗数据,并使用描述性统计分析进行呈现。
共纳入 244 名受试者,其中女性占 58.15%(p < 0.03),包括糖尿病患者 56.96%(n = 139)和高血压患者 43.03%(n = 105)。调整后,60.24%的患者接受单一药物治疗。糖尿病患者使用二甲双胍类(26.92%)、胰岛素(20.0%)和磺脲类(10.0%)治疗,而高血压患者使用钙通道阻滞剂(27.36%)、血管紧张素转换酶抑制剂(21.05%)、血管紧张素Ⅱ受体阻滞剂(16.84%)、利尿剂(7.36%)和β-肾上腺素能受体阻滞剂(3.15%)治疗。总的来说,23.00%的患者出现了不良反应,其中大多数(90.38%)向卫生专业人员报告,23.52%的患者暂时中断或试图改变治疗方案。报告最多的不良反应是胃肠道问题(11.11%),其次是头痛、头晕和耳鸣(6.66%)以及乏力、恶心和头晕(5.33%)。
管理糖尿病和高血压需要应对许多公共挑战,需要更多的关注和兴趣,特别是在偏远地区的文盲人群中。为帮助应对这一问题,可以考虑采取一些新的创新措施、随访和不良反应监测系统。