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中国一例胃癌患者的 Eggerthia catenaformis 菌血症的首次报告。

First report of bacteremia caused by Eggerthia catenaformis in a patient with gastric malignancy in China.

机构信息

Department of Clinical Laboratory, Harbin Medical University Cancer Hospital, 150 Haping Road, Harbin, 150081, China.

Department of Clinical Laboratory, Harbin Medical University Cancer Hospital, 150 Haping Road, Harbin, 150081, China.

出版信息

Anaerobe. 2020 Aug;64:102218. doi: 10.1016/j.anaerobe.2020.102218. Epub 2020 Jul 4.

Abstract

Bacteremia caused by Eggerthia catenaformis is a rarely reported pathogen in cancer patients. Herein, we report a case of bacteremia caused by E.catenaformis in a patient with gastric cancer in China. The patient was a 55-year-old man, diagnosed with gastric cancer more than one month ago, with intermittent fever at a maximum of 39.5 °C for more than half a month. He received symptomatic and supportive treatment after admission to our hospital; a rare anaerobic microorganism, E. catenaformis was isolated from an anaerobic blood culture sample taken from the patient. The antimicrobial susceptibility testing was performed after the isolates were successfully identified by MALDI-TOF MS and 16S rRNA sequencing. The patient was then successfully treated for the bacteremia with metronidazole. To the best of our knowledge, this is the first report of E. catenaformis bacteremia in a patient with cancer.

摘要

由 Eggerthia catenaformis 引起的菌血症是癌症患者中一种罕见的病原体。在此,我们报告了一例中国胃癌患者由 E. catenaformis 引起的菌血症。该患者为 55 岁男性,一个多月前被诊断为胃癌,持续发热半个多月,最高体温达 39.5°C 以上。他入院后接受了对症和支持治疗;从患者的厌氧血培养样本中分离出一种罕见的厌氧微生物,E. catenaformis。在 MALDI-TOF MS 和 16S rRNA 测序成功鉴定分离株后进行了药敏试验。然后,患者成功地用甲硝唑治疗了菌血症。据我们所知,这是首例癌症患者 E. catenaformis 菌血症的报告。

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