Knight Alan, Blewitt Ian, Al-Nuaimi Nassr, Watson Tim, Herzog Dylan, Festy Frederic, Patel Shanon, Foschi Federico, Koller Garrit, Mannocci Francesco
Department of Endodontics, Faculty of Dentistry, Oral and Craniofacial Sciences, Floor 22 Tower Wing, Guy's Dental Hospital, London SE1 9RT, UK.
Department of Conservative Dentistry, College of Dentistry, University of Baghdad, Baghdad 10001, Iraq.
J Clin Med. 2020 Jul 3;9(7):2086. doi: 10.3390/jcm9072086.
The aim of this longitudinal, one-year cohort study was to explore the hypothesis that fluorescence sampling of the root canal space prior to obturation could predict the outcome of root canal treatment (RCT).
Sixty-five teeth underwent primary RCT and were followed up clinically and radiographically. The outcome was determined radiographically with periapical radiographs (PR) and cone beam computed tomography (CBCT) scans.
Success at 12 months was predictable based on the fluorescence score. When the fluorescence score (defined as the percentage of signal over total signal including background) was lower than 67, there was a 4.5 times (Odds ratio (OR) = 0.028; 95% confidence interval (CI): 0.003, 0.291, = 0.001) greater chance of success (90% overall). When the readings were above this threshold, the success rate was 20%.
A chairside sampling method is able to predict the outcome of RCT, through the use of paper point sampling and fluorescence staining. This has reduced the prevalence of persistent infections by guiding the optimum time for obturation. ClinicalTrials.gov trial NCT03660163.
这项为期一年的纵向队列研究旨在探讨在根管充填前对根管空间进行荧光采样能否预测根管治疗（RCT）结果的假设。
65颗牙齿接受了初次根管治疗，并进行了临床和影像学随访。通过根尖片（PR）和锥形束计算机断层扫描（CBCT）扫描进行影像学评估结果。
基于荧光评分可预测12个月时的治疗成功情况。当荧光评分（定义为信号占包括背景在内的总信号的百分比）低于67时，成功几率高出4.5倍（优势比（OR）=0.028；95%置信区间（CI）：0.003，0.291，P=0.001）（总体成功率为90%）。当读数高于此阈值时，成功率为20%。
一种椅旁采样方法能够通过使用纸尖采样和荧光染色来预测根管治疗的结果。通过指导最佳充填时间，降低了持续性感染的发生率。ClinicalTrials.gov试验编号NCT03660163。
