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胰体尾切除术加或不加脾脏保留术后胰瘘的风险。

Postoperative risk of pancreatic fistula after distal pancreatectomy with or without spleen preservation.

机构信息

Division of Oncologic and Minimally-invasive Surgery, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.

出版信息

Tumori. 2021 Apr;107(2):160-165. doi: 10.1177/0300891620936744. Epub 2020 Jul 8.

Abstract

INTRODUCTION

Outcomes after distal pancreatectomy with or without splenectomy are controversial. The present study aims to investigate differences in short-term and long-term outcomes between spleen-preserving distal pancreatectomy (SPDP) and distal pancreatectomy with splenectomy (DPS).

METHODS

In this retrospective review of consecutive patients undergoing distal pancreatectomy with or without splenectomy from January 2011 until December 2017 for benign disease, the primary endpoint was to compare postoperative pancreatic fistula (POPF). The secondary endpoint was to compare duration of surgery, intraoperative blood loss, postoperative complications, length of hospital stay, and long-term outcomes.

RESULTS

Patients undergoing SPDP had a lower rate of POPF (13.6% vs 46.1%; = 0.02). Patients undergoing SPDP (n = 22) were discharged earlier than patients undergoing DPS (n = 26) (8 [4-29] vs 12 [6.48] days; = 0.003). No differences in other intraoperative and postoperative outcomes were found between groups.

CONCLUSION

Patients undergoing SPDP developed fewer POPF and were discharged earlier compared to patients undergoing DPS.

摘要

简介

保留脾脏的胰体尾切除术(SPDP)与胰体尾切除术加脾切除术(DPS)的术后结果仍存在争议。本研究旨在探讨两种术式治疗良性疾病的短期和长期结果的差异。

方法

本回顾性研究连续纳入 2011 年 1 月至 2017 年 12 月期间因良性疾病行胰体尾切除术(伴或不伴脾切除术)的患者,主要终点为比较术后胰瘘(POPF)的发生率。次要终点为比较手术时间、术中出血量、术后并发症、住院时间和长期结果。

结果

SPDP 组的 POPF 发生率较低(13.6% vs 46.1%; = 0.02)。SPDP 组(n = 22)的出院时间早于 DPS 组(n = 26)(8 [4-29] vs 12 [6.48]天; = 0.003)。两组在其他术中及术后结果方面无差异。

结论

与 DPS 相比,SPDP 术后发生 POPF 的风险更低,患者出院更早。

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