Monash Department of Clinical Epidemiology, Cabrini Institute, Monash University, Clayton, Victoria, Australia
Cabrini Institute, Cabrini Health, Malvern, Victoria, Australia.
BMJ Open. 2020 Jul 6;10(7):e037283. doi: 10.1136/bmjopen-2020-037283.
Examining patient and public understanding of overtesting and overdiagnosis (OverTD) is vital for reducing the burden of OverTD. Studies from disparate contexts, disciplines and focusing on disparate healthcare issues have examined patient and public understanding of OverTD. A synthesis is needed to bring this literature together, examine common themes, strengthen conclusions and identify gaps. This will help steer further research, policy and practice to improve patient and public understanding of OverTD. The objective of this study is to synthesise qualitative research data about patient and public understanding of OverTD.
A thematic meta-synthesis will be used to synthesise primary qualitative research and qualitative components of primary mixed-methods research about patient and public understanding of OverTD. Studies published in English will be included. These will be identified using systematic searches from inception to March 2020 in the Scopus, CINAHL, PsycINFO and MEDLINE databases. Studies that satisfy eligibility criteria will be assessed for methodological quality using the Critical Appraisal Skills Programme (CASP) checklist. Thematic meta-synthesis will comprise three stages: (1) line-by-line coding; (2) generation of descriptive themes and (3) generation of analytic themes. Confidence in the synthesis findings will be assessed using the Grading of Recommendations Assessment, Development and Evaluation Confidence in Evidence (GRADE CERQual) approach. A summary of GRADE CERQual results will be presented alongside the key themes. Study eligibility screening, data extraction, analysis and the CASP and GRADE CERQual assessments will be undertaken independently by two review authors.
Ethics approval is not required for this secondary analysis of published data. The results will be disseminated in peer-reviewed journals and may be presented in conference papers and elsewhere.
CRD42020156838.
检查患者和公众对过度检测和过度诊断（OverTD）的理解对于减轻 OverTD 的负担至关重要。来自不同背景、学科的研究以及关注不同医疗保健问题的研究都考察了患者和公众对 OverTD 的理解。需要进行综合分析，将这些文献汇集在一起，检查共同的主题，加强结论并确定差距。这将有助于指导进一步的研究、政策和实践，以提高患者和公众对 OverTD 的理解。本研究的目的是综合关于患者和公众对 OverTD 的理解的定性研究数据。
将使用主题元分析综合关于患者和公众对 OverTD 的理解的定性研究和定性部分的主要混合方法研究。纳入发表于英文期刊的研究。将通过系统搜索从起始时间到 2020 年 3 月在 Scopus、CINAHL、PsycINFO 和 MEDLINE 数据库中确定这些研究。使用关键评估技能计划（CASP）检查表评估符合入选标准的研究的方法学质量。主题元分析将包括三个阶段：（1）逐行编码；（2）生成描述性主题；（3）生成分析性主题。使用推荐评估、制定和评估分级（GRADE）置信度评估方法（GRADE CERQual）评估综合发现的置信度。将使用 GRADE CERQual 结果摘要以及关键主题一起呈现。研究入选标准筛查、数据提取、分析以及 CASP 和 GRADE CERQual 评估将由两位综述作者独立进行。
这是对已发表数据的二次分析，不需要伦理批准。结果将在同行评议期刊上发表，也可能在会议论文和其他地方呈现。
PROSPERO 注册号：CRD42020156838。
