All India Institute of Medical Sciences Mangalagiri.
Mahatma Gandhi Medical College and Research Institutesri Balaji Vidyapeeth.
Otolaryngol Pol. 2020 Feb 20;74(4):37-40. doi: 10.5604/01.3001.0013.8593.
<b>Background:</b> Mucormycosis is a rare fungal infection affecting people with impaired immunity. The aim of this study is to shed light on the epidemiology, incidence, and outcome of patients with mucormycosis hospitalized at a tertiary care center in Pondicherry. <br><b>Methods:</b> We conducted a retrospective chart review between January 2008 and January 2018. All patients with proven or probable mucormycosis were included. <br><b>Results:</b> A total of 24 patients were included. Their median age was 49 years and the majority were males. Comorbidities included mainly hematologic malignancy and diabetes mellitus. A liposomal amphotericin B formulation alone or in combination with other antifungals was used as a first line agent in all patients. <br><b>Conclusion:</b> The incidence of mucormycosis has significantly increased over the past 10 years at our institution, most likely due to increased risk factors.
毛霉菌病是一种罕见的真菌感染，影响免疫功能受损的人群。本研究旨在阐明在本地一家三级护理中心住院的毛霉菌病患者的流行病学、发病率和结局。
我们进行了一项回顾性图表审查，时间范围为 2008 年 1 月至 2018 年 1 月。所有确诊或疑似毛霉菌病的患者均被纳入研究。
共纳入 24 例患者。他们的中位年龄为 49 岁，大多数为男性。合并症主要包括血液系统恶性肿瘤和糖尿病。所有患者均单独使用或联合其他抗真菌药物使用脂质体两性霉素 B 制剂作为一线药物。
在过去 10 年中，我院毛霉菌病的发病率显著增加，这很可能是由于危险因素的增加。
