Imafuku Hikaru, Komatsu Junya, Imai Ryuichiro, Ohsawa Naoto, Nakaoka Yoko, Kubokawa Sho-Ichi, Kawai Kazuya, Hamashige Naohisa, Doi Yoshinori
The Department of Medicine, Chikamori Hospital, Kochi, Japan.
Cardiomyopathy Institute, Chikamori Hospital, Ohkawasuji 1-1-16, Kochi-shi, Japan.
J Cardiol Cases. 2020 May 1;22(1):15-18. doi: 10.1016/j.jccase.2020.03.011. eCollection 2020 Jul.
Aortic stenosis is occasionally associated with subvalvular obstruction and remaining obstruction may at times be found after aortic valve replacement.
A 69-year-old woman with a history of several episodes of unconsciousness was admitted because of exertional chest oppression. The echocardiography revealed severe aortic stenosis (flow velocity 6.2 m/sec, maximum / mean pressure gradient 152 / 99 mmHg, valve area 0.59 cm2) as well as gradient within the left ventricular cavity from the mid ventricular level (flow velocity 4.5 m/sec, maximum gradient 82 mmHg). Despite aortic valve replacement and concomitant septal myectomy which was thought adequate in reducing subvalvular pressure gradient during surgery, postoperative echocardiography revealed significant residual mid ventricular gradient (flow velocity 4.9 m/sec, maximum gradient 95 mmHg). It was decided to implant dual-chamber pacemaker, which resulted in significant reduction of residual mid ventricular gradient (flow velocity 1.4 m/sec, maximum gradient 8 mmHg).
Dual-chamber pacing was extremely effective in reducing residual mid ventricular gradient in a patient who underwent aortic valve replacement and concomitant septal myectomy for severe aortic stenosis and subvalvular obstruction.<: Dual-chamber pacing was extremely effective in reducing residual mid-ventricular pressure gradient in a 69-year-old woman with antecedent aortic valve replacement and concomitant septal myectomy for severe aortic stenosis and subvalvular obstruction.Dual-chamber pacing may have the potential to become one of the non-surgical therapeutic options for those with post-surgical residual subvalvular gradient, not only for severe aortic stenosis and subvalvular obstruction but also for obstructive hypertrophic cardiomyopathy.>.
主动脉瓣狭窄偶尔会伴有瓣下梗阻,并且在主动脉瓣置换术后有时会发现仍存在梗阻。
一名69岁有多次意识丧失发作史的女性因劳力性胸部压迫感入院。超声心动图显示严重主动脉瓣狭窄(血流速度6.2米/秒,最大/平均压力阶差152/99毫米汞柱,瓣口面积0.59平方厘米)以及左心室腔内从中部心室水平起的压力阶差(血流速度4.5米/秒,最大压力阶差82毫米汞柱)。尽管进行了主动脉瓣置换术并同期行室间隔心肌切除术,术中认为该手术足以降低瓣下压力阶差,但术后超声心动图显示仍存在显著的心室中部残余压力阶差(血流速度4.9米/秒,最大压力阶差95毫米汞柱)。决定植入双腔起搏器,结果显著降低了心室中部残余压力阶差(血流速度1.4米/秒,最大压力阶差8毫米汞柱)。
对于一名因严重主动脉瓣狭窄和瓣下梗阻接受主动脉瓣置换术并同期行室间隔心肌切除术的患者,双腔起搏在降低心室中部残余压力阶差方面极其有效。双腔起搏可能有潜力成为那些术后存在瓣下残余压力阶差患者的非手术治疗选择之一,不仅适用于严重主动脉瓣狭窄和瓣下梗阻,也适用于梗阻性肥厚型心肌病。