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孕早期阴道出血孕妇的预后:布琼布拉卡门盖大学医院约239例病例

[Prognosis of pregnant women with vaginal bleeding during the first trimester: about 239 cases at the Kamenge University Hospital in Bujumbura].

作者信息

Birindwa Etienne Kajibwami, Sindayirwanya Jean-Baptiste, Harerimana Salvatore

机构信息

Université Catholique de Bukavu, Bugabo 02, Avenue de la Mission, Commune de Kadutu Bukavu, République Démocratique du Congo.

Université du Burundi, Avenue de l'Unesco numéro 2, BP 1550 Bujumbura, Burundi.

出版信息

Pan Afr Med J. 2020 Apr 9;35:111. doi: 10.11604/pamj.2020.35.111.20413. eCollection 2020.

DOI:10.11604/pamj.2020.35.111.20413
PMID:32637009
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7320776/
Abstract

The purpose of this study is to evaluate the post-discharge prognosis of pregnant women with vaginal bleeding during the first trimester, admitted to the Emergency Maternity at the Kamenge University Hospital (CHUK), according to patients age, amount of bleeding and ultrasound results. We conducted a retrospective descriptive and analytical study of 239 medical records of patients hospitalized over a period of six years from January 2012 to December 2017. In this study, the prognosis of pregnant women with first-trimester metrorrhagia hospitalized at the CHUK was bad; the majority of them (65.7%) had miscarriage. Amount of bleeding, maternal age below 20 years, or well above or equal to 35 years, were significant risk factors but much more ultrasound detection of trophoblastic detachment. It would be interesting to perform a prospective study to detect the causes of these metrorrhagias and to determine late pregnancy complications.

摘要

本研究的目的是根据患者年龄、出血量和超声检查结果,评估在卡门格大学医院(CHUK)急诊产科收治的孕早期阴道出血孕妇出院后的预后情况。我们对2012年1月至2017年12月期间六年内住院的239例患者的病历进行了回顾性描述性和分析性研究。在本研究中,在CHUK住院的孕早期子宫出血孕妇的预后较差;其中大多数(65.7%)发生了流产。出血量、20岁以下或远高于或等于35岁的产妇年龄是显著的危险因素,但更重要的是超声检测到滋养层分离。进行前瞻性研究以检测这些子宫出血的原因并确定晚期妊娠并发症将是很有意义的。

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1
[Prognosis of pregnant women with vaginal bleeding during the first trimester: about 239 cases at the Kamenge University Hospital in Bujumbura].孕早期阴道出血孕妇的预后:布琼布拉卡门盖大学医院约239例病例
Pan Afr Med J. 2020 Apr 9;35:111. doi: 10.11604/pamj.2020.35.111.20413. eCollection 2020.
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Retrospective Study of First Trimester Metrorrhagia: Pregnancy Follow-Up and Relationship with the Appearance of Gestational Complications.回顾性研究早孕期子宫出血:妊娠随访及与妊娠并发症出现的关系。
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[Prognostic significance of subchorionic hematoma for the course of pregnancy].[绒毛膜下血肿对妊娠过程的预后意义]
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[Metrorrhagia during the second trimester of pregnancy: obstetrical and perinatal outcome. A retrospective study including 85 cases].[妊娠中期子宫出血:产科及围产期结局。一项纳入85例病例的回顾性研究]
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Rate of spontaneous abortion after first trimester sonographic demonstration of fetal cardiac activity.孕早期超声显示胎儿心脏活动后的自然流产率。
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Pitfalls in first-trimester bleeding.孕早期出血的陷阱。
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本文引用的文献

1
Prediction of miscarriage in women with viable intrauterine pregnancy-A systematic review and diagnostic accuracy meta-analysis.宫内妊娠存活女性流产的预测——一项系统评价与诊断准确性的Meta分析
Eur J Obstet Gynecol Reprod Biol. 2018 Jan;220:122-131. doi: 10.1016/j.ejogrb.2017.10.024. Epub 2017 Nov 4.
2
Signs and Symptoms of Early Pregnancy Loss.早期妊娠丢失的体征和症状。
Reprod Sci. 2017 Apr;24(4):502-513. doi: 10.1177/1933719116654994. Epub 2016 Sep 27.
3
How can we better predict the risk of spontaneous miscarriage among women experiencing threatened miscarriage?
我们如何能更好地预测有先兆流产经历的女性发生自然流产的风险?
Gynecol Endocrinol. 2015;31(8):647-51. doi: 10.3109/09513590.2015.1031103. Epub 2015 Jun 2.
4
Are abnormal yolk sac characteristics important factors in abortion rates?异常卵黄囊特征是导致流产率的重要因素吗?
Int J Fertil Steril. 2012 Jul;6(2):127-30. Epub 2012 Jun 19.
5
[Epidemiology of loss pregnancy].[复发性流产的流行病学]
J Gynecol Obstet Biol Reprod (Paris). 2014 Dec;43(10):764-75. doi: 10.1016/j.jgyn.2014.09.011. Epub 2014 Nov 6.
6
Diagnostic criteria for nonviable pregnancy early in the first trimester.孕早期不可避免流产的诊断标准。
Ultrasound Q. 2014 Mar;30(1):3-9. doi: 10.1097/RUQ.0000000000000060.
7
ACR appropriateness Criteria® first trimester bleeding.美国放射学会适宜性标准®:孕早期出血
Ultrasound Q. 2013 Jun;29(2):91-6. doi: 10.1097/RUQ.0b013e31829158c2.
8
First trimester vaginal bleeding and adverse pregnancy outcomes among Chinese women: from a large cohort study in China.中国女性孕早期阴道出血与不良妊娠结局:来自中国一项大型队列研究
J Matern Fetal Neonatal Med. 2012 Aug;25(8):1297-301. doi: 10.3109/14767058.2011.632034. Epub 2011 Nov 22.
9
A model and scoring system to predict outcome of intrauterine pregnancies of uncertain viability.预测不明存活能力的宫内妊娠结局的模型和评分系统。
Ultrasound Obstet Gynecol. 2011 May;37(5):588-95. doi: 10.1002/uog.9007.
10
Perinatal outcomes in women with subchorionic hematoma: a systematic review and meta-analysis.围生期结局与胎盘绒毛膜下血肿:系统评价与荟萃分析。
Obstet Gynecol. 2011 May;117(5):1205-1212. doi: 10.1097/AOG.0b013e31821568de.