Bäck Malin, Falkenström Fredrik, Gustafsson Sanna Aila, Andersson Gerhard, Holmqvist Rolf
Department of Behavioural Sciences and Learning, Linköping University, Linköping, Sweden.
Futurum: Academy for Health and Care, Jönköping, Region Jönköping County Sweden.
J Eat Disord. 2020 Jul 3;8:33. doi: 10.1186/s40337-020-00308-1. eCollection 2020.
Interpersonal psychotherapy (IPT) can be effective for both Bulimia Nervosa (BN) and co-occurring depression. While changes in symptoms of Eating disorder (ED) and depression have been found to correlate, it is unclear how they interact during treatment and in which order the symptoms decrease.
Thirty-one patients with BN and depressive symptoms received IPT using the manual IPT-BNm in a naturalistic design. The outcome was measured with the Eating Disorder Examination Questionnaire (EDE-Q) and the Montgomery Åsberg Depression Rating Scale (MADRS-S). Symptom improvement at each session was measured with Repeated Evaluation of Eating Disorder Symptoms (REDS) and the Patient Health Questionnaire-9 (PHQ-9).
Significant improvements with large effect sizes were found on both ED symptoms and depression. The rates of change were linear for both BN and depression. A strong correlation between reduction of depressive symptoms and ED symptoms was found. Depressive symptom reduction at one session predicted improvement of ED symptoms at the next session.
IPT-BNm had an effect on both BN and co-occurring depressive symptoms. The analyses indicated that reduction in depressive symptoms preceded reduction in bulimic symptoms.
人际心理治疗（IPT）对神经性贪食症（BN）和并发抑郁症均有效。虽然已发现饮食失调（ED）症状和抑郁症状的变化存在相关性，但尚不清楚它们在治疗过程中如何相互作用以及症状以何种顺序减轻。
31名患有BN和抑郁症状的患者采用自然主义设计，使用IPT-BNm手册接受IPT治疗。结局通过饮食失调检查问卷（EDE-Q）和蒙哥马利-Åsberg抑郁评定量表（MADRS-S）进行测量。每次治疗时的症状改善情况通过饮食失调症状重复评估（REDS）和患者健康问卷-9（PHQ-9）进行测量。
在ED症状和抑郁症状方面均发现有显著改善，且效应量较大。BN和抑郁症状的变化率均呈线性。发现抑郁症状减轻与ED症状减轻之间存在强相关性。某一次治疗时抑郁症状的减轻可预测下一次治疗时ED症状的改善。
IPT-BNm对BN和并发的抑郁症状均有效果。分析表明，抑郁症状的减轻先于贪食症状的减轻。
