Jochelson M S, Herman T S, Stomper P C, Mauch P M, Kaplan W D
Department of Radiology, Dana-Farber Cancer Institute, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115.
AJR Am J Roentgenol. 1988 Dec;151(6):1229-31. doi: 10.2214/ajr.151.6.1229.
Detection of all sites of lymphoma is imperative for accurate planning of radiation therapy. In patients with Hodgkin disease, mantle radiation is used to treat the thoracic lymph nodes; in those with early-stage or nonbulky disease, mantle and paraaortic radiation may be the only treatment given. CT scanning of the chest adds important information to that obtained from chest radiographs. Gallium-67 scintigraphy has also been used to provide additional information on sites of active tumor. To determine the usefulness of 67Ga-citrate scintigraphy in planning the portals for radiation therapy, we analyzed the radiation treatment plans in 26 consecutive patients with Hodgkin disease; in all 26 patients, the disease had been staged by chest radiographs, chest CT scans, and gallium-67 images. Gallium-67 imaging alone provided unique information that affected the treatment plans in three patients (12%). The combined results of gallium-67 imaging and CT scans influenced the planning of radiation therapy in eight patients (31%). Gallium-67 imaging was found to be an important adjunctive study for optimal planning of radiation therapy in patients with Hodgkin disease.
准确规划放射治疗时，检测淋巴瘤的所有部位至关重要。对于霍奇金病患者，斗篷野放疗用于治疗胸部淋巴结；对于早期或肿块较小的疾病患者，斗篷野和腹主动脉旁放疗可能是唯一的治疗方法。胸部CT扫描为胸部X线片提供了重要补充信息。镓-67闪烁扫描也用于提供有关活跃肿瘤部位的额外信息。为了确定柠檬酸镓-67闪烁扫描在规划放射治疗野方面的作用，我们分析了连续26例霍奇金病患者的放射治疗计划；所有26例患者均通过胸部X线片、胸部CT扫描和镓-67图像进行了分期。仅镓-67成像就提供了独特信息，影响了3例患者（12%）的治疗计划。镓-67成像和CT扫描的综合结果影响了8例患者（31%）的放射治疗计划。镓-67成像被发现是霍奇金病患者优化放射治疗计划的重要辅助检查。
