Stomper P C, Cholewinski S P, Park J, Bakshi S P, Barcos M P
Department of Diagnostic Radiology, Roswell Park Cancer Institute, School of Medicine, Buffalo, NY.
Radiology. 1993 May;187(2):381-6. doi: 10.1148/radiology.187.2.8475277.
A retrospective study was performed to assess whether lymphangiography and gallium-67 scanning were complementary to computed tomography (CT) in abdominal staging of disease in 94 patients with early-stage thoracic Hodgkin disease. In 51 patients with surgical or follow-up correlation, the spleen was involved in 16% (n = 8), the spleen and lymph nodes in 22% (n = 11), and only lymph nodes in 2% (n = 1). In these 51 patients, none of the imaging modalities had greater than 50% sensitivity for the detection of nodal involvement. The overall accuracy was similar (71%-82%) for each modality. Analysis of subgroups of patients with lymph nodes measuring less than 10 mm, 10-19 mm, or 20 mm or greater at CT revealed that lymphangiography and gallium scanning added little to the positive or negative predictive values of CT. The sensitivity of CT for detection of splenic disease was 11% (two of 19). On the basis of surgical or follow-up correlation in 51 patients, the authors conclude that lymphangiography and gallium scanning offer minimal or no complementary benefit.
进行了一项回顾性研究，以评估淋巴管造影和镓-67扫描在94例早期胸段霍奇金病患者的腹部疾病分期中是否可作为计算机断层扫描（CT）的补充。在51例有手术或随访对照的患者中，脾脏受累的占16%（n = 8），脾脏和淋巴结均受累的占22%（n = 11），仅淋巴结受累的占2%（n = 1）。在这51例患者中，对于检测淋巴结受累，没有一种成像方式的敏感性超过50%。每种方式的总体准确性相似（71%-82%）。对CT检查时淋巴结小于10mm、10-19mm或20mm及以上的患者亚组分析显示，淋巴管造影和镓扫描对CT的阳性或阴性预测值几乎没有增加。CT检测脾脏疾病的敏感性为11%（19例中有2例）。基于51例患者的手术或随访对照，作者得出结论，淋巴管造影和镓扫描提供的补充益处极小或没有。
