Shewade H D, Gupta V, Satyanarayana S, Chadha S S, Pandurangan S, Mohanty S, Kumar A M V
International Union Against Tuberculosis and Lung Disease (The Union), Paris, France.
The Union South-East Asia (USEA), New Delhi, India.
Public Health Action. 2020 Jun 21;10(2):53-56. doi: 10.5588/pha.19.0057.
Among new smear-positive pulmonary tuberculosis (TB) patients aged ⩾15 years from marginalised populations in India, one in four had a history of a household member with TB and one in 10 had a TB-related death in the household. This contribution of household transmission to overall TB transmission provides evidence for a potential population-level benefit of TB preventive treatment for all household contacts (without active TB). Females with TB had a significantly higher household TB exposure than males. Targeted TB preventive treatment (if implemented in a phased manner) among female household contacts may be explored after considering other factors.
在印度边缘化人群中，年龄≥15岁的新涂片阳性肺结核（TB）患者中，四分之一的人有家庭成员患过结核病，十分之一的人有家庭成员死于结核病。家庭传播对总体结核病传播的这种影响为对所有家庭接触者（无活动性结核病）进行结核病预防性治疗可能带来的潜在人群层面益处提供了证据。患结核病的女性家庭结核病暴露率明显高于男性。在考虑其他因素后，可探索对女性家庭接触者进行有针对性的结核病预防性治疗（若分阶段实施）。
