Department of Biochemistry, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia.
Department of Biochemistry, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Virol J. 2020 Jul 8;17(1):96. doi: 10.1186/s12985-020-01363-5.
Coronaviruses are large family-RNA viruses that belong to the order Nidovirales, family Coronaviridae, subfamily Coronavirinae. The novel COVID-19 infection, caused by a beta coronavirus called SARS-CoV-2, is a new outbreak that has been emerged in Wuhan, China in December 2019. The most common symptoms of COVID-19 are fever, cough, and dyspnea. As per the March 12, 2020, WHO report, more than 125,048 confirmed COVID-19 cases and over 4613 deaths have been identified in more than 117 countries. It is now regarded as a pandemic that seriously spread and attack the world. The primary means of transmission is person to person through droplets that occurred during coughing or sneezing, through personal contact (shaking hands), or by touching contaminated objects. So far, there is no effective therapy and vaccine available against this novel virus and therefore, only supportive care is used as the mainstay of management of patients with COVID-19. The mortality rate of COVID-19 is considerable. This work aimed to provide insight on the newly emerged COVID-19, in the hope to gain a better understanding on the general overview, epidemiology, transmission, clinical features, diagnosis, treatment, and clinical outcomes as well as the prevention and control of COVID-19.
冠状病毒是一种大型 RNA 病毒，属于 Nidovirales 目、冠状病毒科、冠状病毒亚科。由一种称为 SARS-CoV-2 的β冠状病毒引起的新型 COVID-19 感染是 2019 年 12 月在中国武汉爆发的新疫情。COVID-19 的最常见症状是发热、咳嗽和呼吸困难。根据 2020 年 3 月 12 日世界卫生组织的报告，在 117 多个国家已经发现超过 125048 例确诊的 COVID-19 病例和超过 4613 例死亡。它现在被认为是一种严重传播和袭击世界的大流行疾病。主要传播途径是通过咳嗽或打喷嚏时产生的飞沫、人际接触（握手）或接触污染物体进行人际传播。到目前为止，还没有针对这种新型病毒的有效治疗方法和疫苗，因此，只能使用支持性护理作为 COVID-19 患者管理的主要方法。COVID-19 的死亡率相当高。这项工作旨在提供对新出现的 COVID-19 的深入了解，希望更好地了解其概述、流行病学、传播、临床特征、诊断、治疗以及临床结果，以及 COVID-19 的预防和控制。
