Department of Dermatology, North Delhi Municipal Corporation Medical College & Hindu Rao Hospital, New Delhi, India.
Department of Dermatology, LTM Medical College and General Hospital, Mumbai, India.
Dermatol Ther. 2020 Jul;33(4):e13677. doi: 10.1111/dth.13677. Epub 2020 Jun 26.
The world entered the year 2020 with reports of the emergence of a new viral illness in Wuhan city, Hubei province, China. In January 2020, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was identified to be the causative novel coronavirus for the cluster of patients suffering from pneumonia in China. The disease was later named as coronavirus disease (COVID-19) and was declared a pandemic by the World Health Organization on March 11, 2020. Several studies, since then, have tried to study and explain the origin of SARS-CoV-2, its structure and pathogenicity, epidemiology, modes of transmission, spectrum of illness and causes of mortality and morbidity. The current management strategies focus on supportive care and prevention of complications. With no definite treatment, as of now, encouraging reports of some anti-viral and anti-malarial drugs in the management of COVID-19 generate some hope. This review intends to cover the current known aspects of COVID-19 and SARS-CoV-19, based on the available literature.
世界进入 2020 年之际,有报道称中国湖北省武汉市出现了一种新型病毒性疾病。2020 年 1 月,严重急性呼吸综合征冠状病毒 2(SARS-CoV-2)被确定为导致中国肺炎患者群的新型冠状病毒。该疾病后来被命名为冠状病毒病(COVID-19),并于 2020 年 3 月 11 日被世界卫生组织宣布为大流行。此后,多项研究试图研究和解释 SARS-CoV-2 的起源、结构和致病性、流行病学、传播方式、疾病谱以及死亡率和发病率的原因。目前的管理策略侧重于支持性护理和预防并发症。由于目前尚无明确的治疗方法,一些抗病毒和抗疟药物在 COVID-19 管理中的应用的令人鼓舞的报告带来了一些希望。本综述旨在根据现有文献,涵盖 COVID-19 和 SARS-CoV-19 的当前已知方面。