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澳大利亚墨尔本一家性健康诊所中,尿道淋病检测呈阳性的无症状和有症状异性恋男性的临床表现。

Clinical presentation of asymptomatic and symptomatic heterosexual men who tested positive for urethral gonorrhoea at a sexual health clinic in Melbourne, Australia.

机构信息

Melbourne Sexual Health Centre, Alfred Health, 580 Swanston Street, Carlton, Melbourne, VIC, 3053, Australia.

Preventive Medicine and Public Health Training Unit PSMar-UPF-ASPB, Barcelona, Spain.

出版信息

BMC Infect Dis. 2020 Jul 8;20(1):486. doi: 10.1186/s12879-020-05197-y.

Abstract

BACKGROUND

Asymptomatic screening for gonorrhoea in heterosexual men is currently not recommended in many countries including Australia, given the prevalence is relatively low in the heterosexual population. We aimed to determine the proportion of urethral gonorrhoea cases among heterosexual men attending a sexual health clinic that was asymptomatic and symptomatic, the time since last sexual contact to the onset of symptoms and the time to clinic presentation following the onset of symptoms.

METHODS

This was a cross-sectional study that included heterosexual men aged 16 years or above attending the Melbourne Sexual Health Centre (MSHC) in Australia between August 2017 and August 2018. Gonorrhoea cases were diagnosed by nucleic acid amplification testing (NAAT) and/or culture. Descriptive analyses were conducted for all gonorrhoea cases including demographic characteristics, recent sexual practices, reported urethral symptoms and duration, sexual contact with a person diagnosed with gonorrhoea, investigations performed and laboratory results.

RESULTS

There were 116 confirmed cases of urethral gonorrhoea in heterosexual men over the study period of which 6.0% (95% CI: 2.7-12.1%) were asymptomatic. Typical urethral discharge was present in 80.2% (95% CI: 71.9-86.5%) of men. The mean time between last sexual contact and the onset of symptoms was 7.0 days, and between the onset of symptoms to presentation to the clinic was 5.6 days.

CONCLUSIONS

A small proportion of heterosexual men with urethral gonorrhoea do not have any symptoms. Heterosexual men with urethral symptoms usually seek for healthcare within a week, prompting rapid healthcare-seeking behaviour.

摘要

背景

鉴于异性恋人群中的淋病患病率相对较低,包括澳大利亚在内的许多国家目前不建议对异性恋男性进行无症状淋病筛查。我们旨在确定在性健康诊所就诊的无症状和有症状的异性恋男性中尿道淋病病例的比例、从上次性接触到症状出现的时间以及从症状出现到就诊的时间。

方法

这是一项横断面研究,纳入了 2017 年 8 月至 2018 年 8 月期间在澳大利亚墨尔本性健康中心(MSHC)就诊的年龄在 16 岁及以上的异性恋男性。淋病病例通过核酸扩增检测(NAAT)和/或培养确诊。对所有淋病病例进行描述性分析,包括人口统计学特征、近期性行为、报告的尿道症状和持续时间、与确诊淋病患者的性接触、进行的检查和实验室结果。

结果

在研究期间,共确诊了 116 例异性恋男性的尿道淋病病例,其中 6.0%(95%CI:2.7-12.1%)为无症状。80.2%(95%CI:71.9-86.5%)的男性存在典型的尿道分泌物。从上次性接触到症状出现的平均时间为 7.0 天,从症状出现到就诊的平均时间为 5.6 天。

结论

一小部分患有尿道淋病的异性恋男性没有任何症状。有尿道症状的异性恋男性通常会在一周内寻求医疗保健,促使他们迅速寻求医疗保健。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0462/7346512/82134049b720/12879_2020_5197_Fig1_HTML.jpg

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